Evidence map›Paper›PMID 37202755›Full record

ArticleBMC pregnancy and childbirth2023

Effect of levothyroxine treatment on fetal growth among women with mild subclinical hypothyroidism and thyroid peroxidase antibody negative: a cohort study.

Yuelong Ji, Jinhui Xu, Tao Su, Lizi Lin, Shuang Zhou, Heling Bao, Zheng Liu, Shusheng Luo, Xiangrong Xu, Na Han and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yuelong JiDepartment of Maternal and Child Health, School of Public Health, Peking University, Haidian District, No. 38 Xueyuan Rd, Beijing, 100191, China.
Jinhui XuDepartment of Maternal and Child Health, School of Public Health, Peking University, Haidian District, No. 38 Xueyuan Rd, Beijing, 100191, China.
Tao SuTongzhou Maternal and Child Health Hospital of Beijing, Beijing, China.
Lizi LinDepartment of Occupational and Environmental Health, School of Public Health, Sun Yat-Sen University, Guangzhou, China.
Shuang ZhouDepartment of Maternal and Child Health, School of Public Health, Peking University, Haidian District, No. 38 Xueyuan Rd, Beijing, 100191, China.
Heling BaoDepartment of Maternal and Child Health, School of Public Health, Peking University, Haidian District, No. 38 Xueyuan Rd, Beijing, 100191, China.
Zheng LiuDepartment of Maternal and Child Health, School of Public Health, Peking University, Haidian District, No. 38 Xueyuan Rd, Beijing, 100191, China.
Shusheng LuoDepartment of Maternal and Child Health, School of Public Health, Peking University, Haidian District, No. 38 Xueyuan Rd, Beijing, 100191, China.
Xiangrong XuSchool of Public Health, Peking University, Beijing, China.
Na HanTongzhou Maternal and Child Health Hospital of Beijing, Beijing, China.
Hai-Jun WangDepartment of Maternal and Child Health, School of Public Health, Peking University, Haidian District, No. 38 Xueyuan Rd, Beijing, 100191, China. whjun@pku.edu.cn.
Peking University · CNChongqing Maternal and Child Health Hospital · CNSun Yat-sen University · CN

Funding

National Natural Science Foundation of China 82204055National Natural Science Foundation of China 92046019
6 · The paper itself

Abstract

backgroundSome clinicians used levothyroxine (LT4) treatment for mild subclinical hypothyroidism (SCH) pregnant women (2.5 < thyroid-stimulating hormone (TSH) ≤ the pregnancy-specific reference range with normal free thyroxine (FT4) level) with thyroid peroxidase antibody negative (TPOAb

methodsThis was a birth cohort study including 14,609 pregnant women between 2016 and 2019 in Tongzhou Maternal and Child Health Hospital of Beijing, China. Pregnant women were divided into 3 groups as follows: Euthyroid (n = 14,285, 0.03 ≤ TSH ≤ 2.5mIU/L, normal FT4), TPOAb

resultsThere was no difference in fetal growth indicators and birth weight between the untreated mild SCH women with TPOAb

conclusionsWe observed that LT4 treatment for mild SCH with TPOAb

Indexed as

HypothyroidismPregnancy ComplicationsBirth WeightCohort StudiesFemaleFetal DevelopmentHumansIodide PeroxidasePregnancyThyrotropinThyroxineIodide PeroxidaseThyrotropinThyroxineBirth weightFetal growthLevothyroxineMild subclinical hypothyroidism

Identifiers

PMID37202755
PMCPMC10193713
OpenAlexW4377094562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.