Evidence map›Paper›PMID 37202552›Full record

ArticleNature neuroscience2023

A motor association area in the depths of the central sulcus.

Michael A Jensen, Harvey Huang, Gabriela Ojeda Valencia, Bryan T Klassen, Max A van den Boom, Timothy J Kaufmann, Gerwin Schalk, Peter Brunner, Gregory A Worrell, Dora Hermes and 1 more

Erratum issued Registry-linked trialAbstract read
In one paragraph

Article in Nature neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07024875 (Precision Neuroimaging of Parkinson's Disease), which is not on this map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07024875 recruitingnot on this mapstarted 2025, after this paper: background citation

Precision Neuroimaging of Parkinson's Disease

Typeobservational_patient_registrySponsorWashington University School of MedicineRan2025 to 2031Enrolled120ConditionsParkinsons Disease (PD)
3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Beyond the Homunculus-SCAN-AMN as a Shared Action-Oriented Neural Substrate across Movement Disorders.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Michael A JensenMedical Scientist Training Program, Mayo Clinic, Rochester, MN, USA. jensen.michael1@mayo.edu.ORCID http://orcid.org/0000-0002-5191-7244
Harvey HuangMedical Scientist Training Program, Mayo Clinic, Rochester, MN, USA.
Gabriela Ojeda ValenciaDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Bryan T KlassenNeurology, Mayo Clinic, Rochester, MN, USA.
Max A van den BoomNeurosurgery, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0001-5481-1659
Timothy J KaufmannRadiology, Mayo Clinic, Rochester, MN, USA.
Gerwin SchalkNeurosurgery, Mayo Clinic, Rochester, MN, USA.
Peter BrunnerNeurosurgery, Washington University School of Medicine, St Louis, MO, USA.
Gregory A WorrellDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Dora HermesDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-8683-8909
Kai J MillerNeurosurgery, Mayo Clinic, Rochester, MN, USA. miller.kai@mayo.edu.ORCID http://orcid.org/0000-0002-6687-6422

Funding

Training and DisseminationP41EB018783 · NIBIB · WADSWORTH CENTER · PI Theresa M. Vaughan · 2014 to 2026
$15.4M
Institutional Career Development CoreKL2TR002379 · NCATS · MAYO CLINIC ROCHESTER · PI NILUFER ERTEKIN-TANER · 2017 to 2026
$14.9M
An Ecosystem of Technology and Protocols for Adaptive Neuromodulation Research in HumansU01NS128612 · NINDS · MAYO CLINIC ROCHESTER · PI Peter Brunner, Kai Miller · 2022 to 2026
$4.5M
BCI2000: Software Resource for Adaptive Neurotechnology ResearchU24NS109103 · NINDS · WASHINGTON UNIVERSITY · PI BRUNNER, PETER · 2019 to 2024
$2.8M
BCI2000+: A Software Platform for Adaptive NeurotechnologiesR01EB026439 · NIBIB · WASHINGTON UNIVERSITY · PI BRUNNER, PETER · 2018 to 2022
$1.5M
Dynamics and Causal Functions of Large-Scale Cortical and Subcortical NetworksU01NS108916 · NINDS · WADSWORTH CENTER · PI BRUNNER, PETER, WOLPAW, JONATHAN RICKEL · 2018 to 2019
$1.4M
NCATS NIH HHS KL2 TR002379NIBIB NIH HHS P41 EB018783NIBIB NIH HHS R01 EB026439NINDS NIH HHS U01 NS108916NINDS NIH HHS U01 NS128612NINDS NIH HHS U24 NS109103
6 · The paper itself

Abstract

Cells in the precentral gyrus directly send signals to the periphery to generate movement and are principally organized as a topological map of the body. We find that movement-induced electrophysiological responses from depth electrodes extend this map three-dimensionally throughout the gyrus. Unexpectedly, this organization is interrupted by a previously undescribed motor association area in the depths of the midlateral aspect of the central sulcus. This 'Rolandic motor association' (RMA) area is active during movements of different body parts from both sides of the body and may be important for coordinating complex behaviors.

Indexed as

Motor CortexBrain MappingMovement

Identifiers

PMID37202552
PMCPMC10322697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.