Evidence map›Paper›PMID 37202195›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2023

[Electroacupuncture improves motor function of rats with osteoarthritis by alleviating joint inflammation through the Wnt-7B/β-catenin signaling pathway].

X Zheng, S Gao, H You, H Wang, Y Gao, J Wang, J Li, L Li

Open access · greenAbstract readEnglish Abstract
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

X ZhengChengde Medical College, Chengde 067000, China.
S GaoChengde Medical College, Chengde 067000, China.
H YouChengde Medical College, Chengde 067000, China.
H WangDepartment of Traditional Chinese Medicine, Affiliated Hospital of Chengde Medical College, Chengde 067000, China.
Y GaoDepartment of Orthopedics and Traumatology of Traditional Chinese Medicine, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
J WangChengde Medical College, Chengde 067000, China.
J LiDepartment of Rheumatology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.
L LiDepartment of Rheumatology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.
Affiliated Hospital of Chengde Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effect of electroacupuncture on osteoarthritis in rats and explore the possible mechanism.

methodsThirty SD rats were randomly divided into osteoarthritis model group, electro-acupuncture group and control group (

resultsIn behavioral tests, the rats in the model and electroacupuncture groups had significantly higher LequesneMG scores after modeling than those in the control group (

conclusionElectroacupuncture can alleviate joint pain and improve subchondral bone damage in rats with osteoarthritis by reducing IL-1β levels in the joint cartilage tissue and serum to alleviate joint inflammation and by reducing such cytokines as ADAMTS-7 and MMP-3 via regulating the Wnt-7B/β-catenin signaling pathway.

Indexed as

Cartilage, ArticularElectroacupunctureOsteoarthritisAnimalsbeta CateninInflammationMatrix Metalloproteinase 3RatsRats, Sprague-DawleyWnt Signaling Pathwaybeta CateninMatrix Metalloproteinase 3cartilageelectroacupuncturemotor functionosteoarthritissubchondral bone

Identifiers

PMID37202195
PMCPMC10202793
OpenAlexW4377093328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.