Evidence map›Paper›PMID 37202185›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2023

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C Xu, C Li, S Wang

Open access · greenAbstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

C XuGraduate School, Geriatric Center, First Affiliated Hospital, Anhui University of Traditional Chinese Medicine, Hefei 230031, China.
C LiDepartment of Respiratory Medicine, Geriatric Center, First Affiliated Hospital, Anhui University of Traditional Chinese Medicine, Hefei 230031, China.
S WangDepartment of Respiratory Medicine, Geriatric Center, First Affiliated Hospital, Anhui University of Traditional Chinese Medicine, Hefei 230031, China.
Anhui University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the mechanism of

methodsSerum samples were collected from 40 SD rats treated with

resultsAt the optimal concentration of 20%, treatment with the medicated serum for 24 h significantly lowered the mRNA and protein expressions of TLR4, NF- κB, MUC5AC, MUC7, and MUC8 in CSE- exposed 16HBE cells, and these effects were further enhanced by TLR4 silencing in the cells. In 16HBE cells with TLR4 overexpression, the expressions of TLR4, NF-κB, MUC5AC, MUC7, and MUC8 were significantly increased after CSE exposure and were lowered following treatment with the medicated serum (

conclusionsIn the 16HBE cell model of chronic obstructive pulmonary disease (COPD), treatment with

Indexed as

Cigarette SmokingPulmonary Disease, Chronic ObstructiveAnimalsEpithelial CellsHumansInterleukin-6Interleukin-8MucusNF-kappa BRatsRats, Sprague-DawleyRNA, MessengerSignal TransductionToll-Like Receptor 4Tumor Necrosis Factor-alphaInterleukin-6Interleukin-8NF-kappa BRNA, MessengerTLR4 protein, humanTlr4 protein, ratToll-Like Receptor 4Tumor Necrosis Factor-alphaairway inflammationchronic obstructive pulmonary diseasemucus hypersecretionTLR4/NF-κBYifei Jianpi recipe

Identifiers

PMID37202185
PMCPMC10202789
OpenAlexW4377094721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.