Evidence map›Paper›PMID 37202098›Full record

ArticleZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences2022

Intestinal microecology in mice bearing diethylnitrosamine-induced primary hepatocellular carcinoma.

Wenbin Zhou, Yue Zheng, Jia Shang, Haiyang Wang, Yisha Wang, Huan Lu, Xiaoxi Wang, Meihua Sui

Open access · greenAbstract read
In one paragraph

Article in Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Wenbin Zhou1. Qingdao Medical College, Qingdao University, Qingdao 266071, Shandong Province, China.
Yue Zheng2. School of Basic Medical Sciences, Zhejiang University School of Medicine, Hangzhou 310058, China.
Jia Shang2. School of Basic Medical Sciences, Zhejiang University School of Medicine, Hangzhou 310058, China.
Haiyang Wang2. School of Basic Medical Sciences, Zhejiang University School of Medicine, Hangzhou 310058, China.
Yisha Wang2. School of Basic Medical Sciences, Zhejiang University School of Medicine, Hangzhou 310058, China.
Huan Lu2. School of Basic Medical Sciences, Zhejiang University School of Medicine, Hangzhou 310058, China.
Xiaoxi Wang5. Department of Pathology, the First Affiliated Hospital, Zhejiang University School Medicine, Hangzhou 310003, China.
Meihua Sui2. School of Basic Medical Sciences, Zhejiang University School of Medicine, Hangzhou 310058, China.
Zhejiang Chinese Medical University · CNFirst Affiliated Hospital Zhejiang University · CNQingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the characteristics of intestinal microecology in hepatocellular carcinoma (HCC) model mice.

methodsC57BL/6 male mice aged 2 weeks were divided into normal control group and HCC model group. Mice in HCC model group were exposed to a single intraperitoneal injection of diethylnitrosamine (DEN) 2 weeks after birth; the surviving mice were intraperitoneally injected with 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene (TCPOBOP), once every 2 weeks for 8 times starting from the 4

resultsAlpha diversity analysis showed that all Good's coverage reached the maximum value of 1.00, and the differences in the Observed features, Chao1 index, Shannon index and Simpson index of the intestinal flora of mice between normal control group and HCC model group were all statistically significant (all

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAnimalsBacteriaDiethylnitrosamineMaleMiceMice, Inbred C57BLRNA, Ribosomal, 16SDiethylnitrosamineRNA, Ribosomal, 16S16S rRNA sequencingC57BL/6 mouseDiethylnitrosamineHepatocellular carcinomaIntestinal floraMicrobial community structureSpecies diversity

Identifiers

PMID37202098
PMCPMC10265007
OpenAlexW4297675757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.