Evidence map›Paper›PMID 37201543›Full record

ReviewThe lancet. Healthy longevity2023

The role of population-level preventive care for brain health in ageing.

Behnam Sabayan, Sara Doyle, Natalia S Rost, Farzaneh A Sorond, Kamakshi Lakshminarayan, Lenore J Launer

Abstract readReview
In one paragraph

Review in The lancet. Healthy longevity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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  19. Review
  20. What is brain health?Cerebral circulation - cognition and behavior · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Behnam SabayanDepartment of Neurology, HealthPartners Neuroscience Center, St Paul, MN, USA; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA. Electronic address: bsabayan@umn.edu.
Sara DoylePopulation Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Natalia S RostDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Farzaneh A SorondDepartment of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Kamakshi LakshminarayanDepartment of Neurology, School of Medicine, University of Minnesota, Minneapolis, MN, USA.
Lenore J LaunerLaboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.

Funding

DISCOVERY - Statistics and Analysis CoreU19NS115388 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI Steven M Greenberg, Natalia S Rost · 2019 to 2026
$75.4M
Upper Midwest StrokeNet Regional Coordinating Center (RCC)U24NS107269 · NINDS · UNIVERSITY OF MINNESOTA · PI KAMAKSHI LAKSHMINARAYAN, Christopher Streib · 2018 to 2026
$2.8M
Brain aging and cardiovascular risk factors and diseaseZIAAG007480 · NIA · NATIONAL INSTITUTE ON AGING · PI LAUNER, LENORE J · 2011 to 2025
$2.7M
Cerebral Small Vessels in Motor and Cognitive Decline: Neuroimaging Signatures of Vulnerability & ResilienceRF1NS085002 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SOROND, FARZANEH A · 2022 to 2022
$1.5M
mGlide-Care: A mHealth Partnership with Care Givers to Improve HTN Management in Patients with Cognitive ImpairmentK24AG078506 · NIA · UNIVERSITY OF MINNESOTA · PI KAMAKSHI LAKSHMINARAYAN · 2023 to 2026
$688k
Intramural NIH HHS ZIA AG007480NIA NIH HHS K24 AG078506NINDS NIH HHS RF1 NS085002NINDS NIH HHS U19 NS115388NINDS NIH HHS U24 NS107269
6 · The paper itself

Abstract

Over the past several decades, a worldwide demographic transition has led to an increasing number of older adults with chronic neurological conditions. These conditions, which have a profound effect on the cognitive function and physical ability of older adults, also have a long preclinical phase. This feature provides a unique opportunity to implement preventive measures for high-risk groups and the population as a whole, and therefore to reduce the burden of neurological diseases. The concept of brain health has emerged as the overarching theme to define overall brain function independently of underlying pathophysiological processes. We review the concept of brain health from the ageing and preventive care perspectives, discuss the mechanisms underpinning ageing and brain ageing, highlight the interplay of various forces resulting in deviation from brain health towards brain disease, and provide an overview of strategies to promote brain health with a life-course approach.

Indexed as

BrainCognition

Identifiers

PMID37201543
PMCPMC10339354

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.