Evidence map›Paper›PMID 37201213›Full record

Observational studyRevista medica del Instituto Mexicano del Seguro Social2023

[Cost-effectiveness of treatment of type 2 diabetes mellitus in México].

Diana L Pérez-Lozano, Víctor Manuel Camarillo-Nava, Tarsila Elizabeth Juárez-Zepeda, José Elpidio Andrade-Pineda, Danae Pérez-López, Jorge Armando Reyes-Pacheco, Zuley Margarita Lucho-Gutiérrez, Liliana Carmona-Aparicio

Open access · greenAbstract readEnglish AbstractObservational Study
In one paragraph

Observational study in Revista medica del Instituto Mexicano del Seguro Social, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 5 citations in OpenAlex.

  1. [Association between anthropometric clinical predictors and HOMA-IR].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Article
  2. Functional Yogurt Enriched withMolecules (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Comprehensive study of associated factors with Type 2 Diabetes in Mexico: protocol.Revista medica del Instituto Mexicano del Seguro Social · 2025
    Observational
  6. Review
  7. Estimation of the Burden of Ischemic Heart Disease in the Tabasco Population, Mexico, 2013-2021.International journal of environmental research and public health · 2025
    Observational
  8. Macular edema in retinal fundus images by a computational algorithmRevista medica del Instituto Mexicano del Seguro Social · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Diana L Pérez-LozanoUniversidad Autónoma de México, Programa de Maestría y Doctorado en Ciencias Médicas y Odontológicas y de la Salud, Unidad de posgrado. Ciudad de México, México.ORCID 0000-0001-6400-0016
Víctor Manuel Camarillo-NavaInstituto Mexicano del Seguro Social, Órgano de Operación Administrativa Desconcentrada Norte, Coordinación Auxiliar Médica de Investigación en Salud. Ciudad de México, México.ORCID 0000-0002-4088-2568
Tarsila Elizabeth Juárez-ZepedaUniversidad del Valle de México, Escuela de Ciencias de la Salud, Dirección de Medicina, Campus Coyoacán. Ciudad de México, México.ORCID 0000-0003-3501-9505
José Elpidio Andrade-PinedaInstituto Mexicano del Seguro Social, Unidad de Medicina Familiar N°16, OOAD Norte. Ciudad de México, México.ORCID 0000-0001-9676-1522
Danae Pérez-LópezInstituto Mexicano del Seguro Social, Unidad de Medicina Familiar N°20, OOAD Norte. Ciudad de México, México.ORCID 0000-0001-5756-5078
Jorge Armando Reyes-PachecoInstituto Mexicano del Seguro Social, Unidad de Medicina Familiar. No. 13. Ciudad de México, México.ORCID 0000-0003-2869-7455
Zuley Margarita Lucho-GutiérrezUniversidad del Valle de México, Escuela de Medicina, Campus Coyoacán. Ciudad de México, México.ORCID 0000-0001-5273-8208
Liliana Carmona-AparicioSecretaria de Salud, Instituto Nacional de Pediatría. Laboratorio de Neurociencias. Ciudad de México, México.ORCID 0000-0001-8721-9387
Mexican Social Security Institute · MXUniversidad del Valle de México · MXSecretaria de Salud · MXUniversidad Autónoma de la Ciudad de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Type 2 Diabetes Mellitus (DM2) is a public health and socioeconomic problem, generating direct medical costs for its treatment. Objective: To analyze the cost-effectiveness of monotherapy and bitherapy treatments in patients with DM2. Methods: Cost-effectiveness, observational, ambispective, cross-sectional and analytical analysis of files in a first level medical unit. The data in the cost matrix was executed with the Office Excel 2010 program; the most prescribed drug was identified and compared with monotherapy and bitherapy. Results: The annual direct medical costs of the total population were drug cost $118,561.70MN, hospitalization cost $243,756.00MN, consultation cost $327,414.00MN and clinical trial cost $2416.79MN, obtaining an annual total of $692,148.58MN. metformin was the most indicated in monotherapy (88.4%) and as standard therapy it has higher cost-effectiveness compared to glibenclamide. In bitherapy it was metformin/glibenclamide (35.7%) versus the therapeutics of metformin/NPH insulin, metformin/insulin glargine and metformin/dapagliflozin, which had a better cost-effective result, with an incremental cost effectiveness of -$1,128,428.50MN, -$34,365.00 MN, -$119,848.97MN respectively. Conclusions: Metformin presented a better cost-effectiveness ratio in monotherapy, while in bitherapy it was the metformin/NPH insulin association.

Indexed as

Diabetes Mellitus, Type 2MetforminCost-Benefit AnalysisCross-Sectional StudiesGlyburideHumansHypoglycemic AgentsInsulin, IsophaneMexicoGlyburideHypoglycemic AgentsInsulin, IsophaneMetforminCost Effectivenessdiabetes mellitusHealth Care Costpharmacological treatment

Identifiers

PMID37201213
PMCPMC10396055
OpenAlexW4377093067

What OpenQuestion holds

Texttitle and abstract
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.