Evidence map›Paper›PMID 37200906›Full record

ReviewFrontiers in psychiatry2023

Genetic and neural mechanisms of sleep disorders in children with autism spectrum disorder: a review.

Qi Ji, Si-Jia Li, Jun-Bo Zhao, Yun Xiong, Xiao-Hui Du, Chun-Xiang Wang, Li-Ming Lu, Jing-Yao Tan, Zhi-Ru Zhu

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Qi JiDepartment of Psychology, Army Medical University, Chongqing, China.
Si-Jia LiDepartment of Psychology, Army Medical University, Chongqing, China.
Jun-Bo ZhaoDepartment of Psychology, Army Medical University, Chongqing, China.
Yun XiongDepartment of Psychology, Army Medical University, Chongqing, China.
Xiao-Hui DuDepartment of Psychology, Army Medical University, Chongqing, China.
Chun-Xiang WangDepartment of Psychology, Army Medical University, Chongqing, China.
Li-Ming LuCollege of Educational Sciences, Chongqing Normal University, Chongqing, China.
Jing-Yao TanCollege of Educational Sciences, Chongqing Normal University, Chongqing, China.
Zhi-Ru ZhuDepartment of Psychology, Army Medical University, Chongqing, China.
Army Medical University · CNChongqing Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The incidence of sleep disorders in children with autism spectrum disorder (ASD) is very high. Sleep disorders can exacerbate the development of ASD and impose a heavy burden on families and society. The pathological mechanism of sleep disorders in autism is complex, but gene mutations and neural abnormalities may be involved. Methods: In this review, we examined literature addressing the genetic and neural mechanisms of sleep disorders in children with ASD. The databases PubMed and Scopus were searched for eligible studies published between 2013 and 2023. Results: Prolonged awakenings of children with ASD may be caused by the following processes. Mutations in the Conclusion: Our review revealed that the functional and structural abnormalities of sleep-wake related neural circuits induced by gene mutations are strongly correlated with sleep disorders in children with ASD. Exploring the neural mechanisms of sleep disorders and the underlying genetic pathology in children with ASD is significant for further studies of therapy.

Indexed as

autism spectrum disordergenetic mechanismneural mechanismNREM sleepREM sleepsleep disorderssleep–wake rhythmwakening time

Identifiers

PMID37200906
PMCPMC10185750
OpenAlexW4367679130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.