Evidence map›Paper›PMID 37200482›Full record

Trial reportApplied neuropsychology. Adult

Two-year clinical trial examining the effects of speed of processing training on everyday functioning in adults with human immunodeficiency virus-associated neurocognitive disorder (HAND) and borderline HAND in the U.S. Deep South: Findings of the Think Fast Study.

David E Vance, Pariya L Fazeli, Andres Azuero, Sarah Khalidi, Jennifer S Frank, Virginia G Wadley, James L Raper, Caitlin N Pope, Alexandra E Jacob, Karlene K Ball

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Applied neuropsychology. Adult. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

David E VanceSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0002-0498-6263
Pariya L FazeliSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0001-6629-0010
Andres AzueroSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0001-9883-1424
Sarah KhalidiSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Jennifer S FrankSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Virginia G WadleySchool of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0003-4524-8395
James L RaperThe 1917 (HIV/AIDS) Clinic, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0002-3242-4911
Caitlin N PopeDepartment of Health, Behavior & Society, University of Kentucky, Lexington, KY, USA.ORCID 0000-0003-1576-9763
Alexandra E JacobUAB Department of Psychology, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0002-9164-405X
Karlene K BallUAB Department of Psychology, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0003-1811-9870

Funding

Supplement for Kentucky BIRCWH Program: Training the Next Generation of Women's Health Scholars: Dr. ConnerK12DA035150 · NIDA · UNIVERSITY OF KENTUCKY · PI Thomas E Curry · 2012 to 2026
$9.0M
Pilot CoreP30AG022838 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BALL, KARLENE K · 2003 to 2020
$5.7M
An RCT of Speed of Processing Training in Middle-Aged and Older Adults with HIVR01MH106366 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI VANCE, DAVID E · 2016 to 2020
$2.6M
A Novel Neurorehabilitation Approach for Cognitive Aging with HIVR00AG048762 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WHEELER, PARIYA FAZELI · 2016 to 2018
$747k
NIA NIH HHS P30 AG022838NIA NIH HHS R00 AG048762NIDA NIH HHS K12 DA035150NIMH NIH HHS R01 MH106366
6 · The paper itself

Abstract

Many people living with human immunodeficiency virus (HIV) (PLWH) experience cognitive decline that impairs everyday functioning. Cognitive training approaches, such as speed of processing (SOP) training, may reduce the impact of HIV-Associated Neurocognitive Disorder (HAND) on everyday functioning. In this experimental design study called the Think Fast Study, 216 participants age 40 and older with HAND or borderline HAND were randomized to one of three groups: (1) 10 h of SOP training (

Indexed as

Activities of Daily LivingCognitive DysfunctionCognitive RemediationHIV InfectionsOutcome Assessment, Health CareAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedUnited StatesAIDSbrain fitnesscognitive impairmentcognitive remediation therapycognitive reservecognitive trainingHIV-Associated neurocognitive disorderneuroplasticityspeed of processing

Identifiers

PMID37200482
PMCPMC10656361

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.