Evidence map›Paper›PMID 37200473›Full record

Trial reportThe Australian & New Zealand journal of obstetrics & gynaecology2023

Cost-effectiveness of closed incision negative pressure wound therapy in preventing surgical site infection among obese women giving birth by caesarean section: An economic evaluation (DRESSING trial).

Jennifer A Whitty, Adam P Wagner, Evelyn Kang, David Ellwood, Wendy Chaboyer, Sailesh Kumar, Vicki L Clifton, Lukman Thalib, Brigid M Gillespie

Open access · hybridAbstract readMulticenter StudyPragmatic Clinical Trial
In one paragraph

Trial report in The Australian & New Zealand journal of obstetrics & gynaecology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Abdominal wound dehiscence after appendectomy during pregnancy treated by negative pressure wound therapy with subsequent vaginal delivery: A case report and literature review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Review
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Jennifer A WhittyNorwich Medical School, University of East Anglia, Norwich, UK.ORCID 0000-0002-5886-1933
Adam P WagnerNorwich Medical School, University of East Anglia, Norwich, UK.ORCID 0000-0002-9101-3477
Evelyn KangNational Health and Medical Research Council Centre of Research Excellence in Wiser Wound Care, Menzies Health Institute, Griffith University, Gold Coast, Queensland, Australia.
David EllwoodGold Coast University Hospital, Gold Coast Health, Southport, Queensland, Australia.ORCID 0000-0003-4512-6443
Wendy ChaboyerNational Health and Medical Research Council Centre of Research Excellence in Wiser Wound Care, Menzies Health Institute, Griffith University, Gold Coast, Queensland, Australia.ORCID 0000-0001-9528-7814
Sailesh KumarMater Mothers' Hospital, University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0003-0832-4811
Vicki L CliftonMater Research Institute, University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0002-4892-6748
Lukman ThalibDepartment of Biostatistics, Faculty of Medicine, Istanbul Aydın University, Istanbul, Turkey.ORCID 0000-0002-1211-6495
Brigid M GillespieNational Health and Medical Research Council Centre of Research Excellence in Wiser Wound Care, Menzies Health Institute, Griffith University, Gold Coast, Queensland, Australia.ORCID 0000-0003-3186-5691
Griffith University · AUThe University of Queensland · AUUniversity of East Anglia · GBIstanbul Aydın University · TR

Funding

Australian National Health and Medical Research Council APP1081026National Institute of Health Research (NIHR) Applied Research Collaboration East of England (ARC EoE)
6 · The paper itself

Abstract

backgroundThere is growing evidence regarding the potential of closed incision negative pressure wound therapy (ci-NPWT) to prevent surgical site infections (SSIs) in healing wounds by primary closure following a caesarean section (CS).

aimTo assess the cost-effectiveness of ci-NPWT compared to standard dressings for prevention of SSI in obese women giving birth by CS. MATERIALS AND

methodsCost-effectiveness and cost-utility analyses from a health service perspective were undertaken alongside a multicentre pragmatic randomised controlled trial, which recruited women with a pre-pregnancy body mass index ≥30 kg/m

resultsci-NPWT was associated with AUD$162 (95%CI -$170 to $494) higher cost per person and an additional $12 849 (95%CI -$62 138 to $133 378) per SSI avoided. There was no detectable difference in QALYs between groups; however, there are high levels of uncertainty around both cost and QALY estimates. There is a 20% likelihood that ci-NPWT would be considered cost-effective at a willingness-to-pay threshold of $50 000 per QALY. Per protocol and complete case analyses gave similar results, suggesting that findings are robust to protocol deviators and adjustments for missing data.

conclusionsci-NPWT for the prevention of SSI in obese women undergoing CS is unlikely to be cost-effective in terms of health service resources and is currently unjustified for routine use for this purpose.

Indexed as

Negative-Pressure Wound TherapySurgical Wound InfectionAftercareBandagesCesarean SectionCost-Benefit AnalysisFemaleHumansObesityPatient DischargePregnancyQuality of Lifecaesarean sectioncost-effectivenesseconomic evaluationnegative pressure wound therapysurgical site infection

Identifiers

PMID37200473
PMCPMC10952760
OpenAlexW4377047353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.