Evidence map›Paper›PMID 37199833›Full record

ArticleBrain and behavior2023

Assessment of clinical outcomes in patients with fibromyalgia: Analysis from the UK Medical Cannabis Registry.

Claire Wang, Simon Erridge, Carl Holvey, Ross Coomber, Azfer Usmani, Mohammed Sajad, Rahul Guru, Wendy Holden, James J Rucker, Michael W Platt and 1 more

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. The Elusive Truth of Cannabinoids for Rheumatic Pain.Current rheumatology reports · 2024
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Claire WangMedical Cannabis Research Group, Department of Surgery and Cancer, Imperial College London, London, UK.ORCID 0000-0002-6010-2629
Simon ErridgeMedical Cannabis Research Group, Department of Surgery and Cancer, Imperial College London, London, UK.
Carl HolveySapphire Medical Clinics, London, UK.
Ross CoomberSapphire Medical Clinics, London, UK.
Azfer UsmaniSapphire Medical Clinics, London, UK.
Mohammed SajadSapphire Medical Clinics, London, UK.
Rahul GuruSapphire Medical Clinics, London, UK.
Wendy HoldenSapphire Medical Clinics, London, UK.
James J RuckerSapphire Medical Clinics, London, UK.
Michael W PlattMedical Cannabis Research Group, Department of Surgery and Cancer, Imperial College London, London, UK.
Mikael H SodergrenMedical Cannabis Research Group, Department of Surgery and Cancer, Imperial College London, London, UK.
London Clinic · GBCancer Research UK · GBKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere are limited therapeutic options for individuals with fibromyalgia. The aim of this study is to analyze changes in health-related quality of life and incidence of adverse events of those prescribed cannabis-based medicinal products (CBMPs) for fibromyalgia.

methodsPatients treated with CBMPs for a minimum of 1 month were identified from the UK Medical Cannabis Registry. Primary outcomes were changes in validated patient-reported outcome measures (PROMs). A p-value of <.050 was deemed statistically significant.

resultsIn total, 306 patients with fibromyalgia were included for analysis. There were improvements in global health-related quality of life at 1, 3, 6, and 12 months (p < .0001). The most frequent adverse events were fatigue (n = 75; 24.51%), dry mouth (n = 69; 22.55%), concentration impairment (n = 66; 21.57%), and lethargy (n = 65; 21.24%).

conclusionCBMP treatment was associated with improvements in fibromyalgia-specific symptoms, in addition to sleep, anxiety, and health-related quality of life. Those who reported prior cannabis use appeared to have a greater response. CBMPs were generally well-tolerated. These results must be interpreted within the limitations of study design.

Indexed as

CannabisFibromyalgiaMedical MarijuanaHumansQuality of LifeUnited KingdomMedical Marijuanacannabidiolfibromyalgiamedical cannabistetrahydrocannabinol

Identifiers

PMID37199833
PMCPMC10338741
OpenAlexW4377010758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.