Evidence map›Paper›PMID 37199764›Full record

ArticleJournal of neurology2023

Eculizumab for the treatment of glycine receptor antibody associated stiff-person syndrome.

Jennifer A McCombe, Bryan T Klassen, Eoin P Flanagan, James W Teener, Anastasia Zekeridou, Sean J Pittock, Andrew McKeon

Open access · hybridAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 3 citations in OpenAlex.

  1. Pediatric stiff-person syndrome and related disorders: A systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Pooled it
  2. Pooled it
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jennifer A McCombeDivision of Neurology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Bryan T KlassenDepartment of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
Eoin P FlanaganDepartment of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
James W TeenerDepartment of Neurology, University of Michigan, Ann Arbor, Michigan, USA.
Anastasia ZekeridouDepartment of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
Sean J PittockDepartment of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
Andrew McKeonDepartment of Neurology, Mayo Clinic, Rochester, Minnesota, USA. McKeon.Andrew@mayo.edu.
Mayo Clinic · USUniversity of Alberta · CAUniversity of Michigan–Ann Arbor · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Stiff-Person SyndromeAntibodies, Monoclonal, HumanizedAutoantibodiesHumansReceptors, GlycineAntibodies, Monoclonal, HumanizedAutoantibodieseculizumabReceptors, Glycine

Identifiers

PMID37199764
PMCPMC10421785
OpenAlexW4377011119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.