Evidence map›Paper›PMID 37199732›Full record

ArticleChronic obstructive pulmonary diseases (Miami, Fla.)2023

Impact of Marijuana Smoking on COPD Progression in a Cohort of Middle-Aged and Older Persons.

Igor Barjaktarevic, Christopher B Cooper, Tracie Shing, Russell G Buhr, Eric A Hoffman, Prescott G Woodruff, M Bradley Drummond, Richard E Kanner, MeiLan K Han, Nadia N Hansel and 8 more

Registry-linked trialOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chronic obstructive pulmonary diseases (Miami, Fla.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01969344 (Subpopulations and Intermediate Outcome Measures in COPD Study), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01969344 active not recruitingnot on this map

Subpopulations and Intermediate Outcome Measures in COPD Study

TypeobservationalSponsorUniversity of North Carolina, Chapel HillRan2010 to 2031Enrolled2,981ConditionsCOPD, Chronic Obstructive Pulmonary Disease, Chronic Bronchitis, Emphysema
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. The Puzzle of Marijuana Use and Forced Vital Capacity.Annals of the American Thoracic Society · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 12 institutions in 3 countries.

Igor BarjaktarevicDivision of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, United States.
Christopher B CooperDivision of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, United States.
Tracie ShingCollaborative Studies Coordinating Center, Department of Biostatistics, Gilling's School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United States.
Russell G BuhrDivision of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, United States.
Eric A HoffmanDepartments of Radiology, Medicine and Bioengineering, University of Iowa, Iowa City, Iowa, United States.
Prescott G WoodruffDivision of Pulmonary and Critical Care Medicine; Department of Medicine, University of California; San Francisco, California, United States.
M Bradley DrummondDivision of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, United States.
Richard E KannerDivision of Respiratory, Critical Care, and Occupational Pulmonary Medicine, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, United States.
MeiLan K HanDivision of Pulmonary and Critical Care Medicine, School of Medicine, University of Michigan, Ann Arbor, Michigan, United States.
Nadia N HanselDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, United States.
Russell P BowlerDivision of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, Colorado, United States.
Gregory L KinneyDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.
Sean JacobsonDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.
Madeline A MorrisCollege of Nursing and Health Sciences, University of Vermont, Burlington, Vermont, United States.
Fernando J MartinezDivision of Pulmonary and Critical Care Medicine, Weill Cornell Medical College, New York, New York, United States.
Jill OharDivision of Pulmonary, Critical Care, Allergy and Immunology, School of Medicine, Wake Forest University, Wake Forest, North Carolina, United States.
David CouperCollaborative Studies Coordinating Center, Department of Biostatistics, Gilling's School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United States.
Donald P TashkinDivision of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, United States.
University of California, Los Angeles · USUniversity of North Carolina at Chapel Hill · USColorado School of Public Health · USCornell University · USJohns Hopkins University · USNational Jewish Health · USUniversity of California, San Francisco · USUniversity of Iowa · USUniversity of Michigan · USUniversity of Utah · USUniversity of Vermont · USWake Forest University · US

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5M
SPIROMICS II: Biological underpinnings of COPD heterogeneity and progressionU01HL137880 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOODRUFF, PRESCOTT G · 2017 to 2021
$27.9M
SPIROMICS GIC SupportU24HL141762 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COUPER, DAVID J, O'NEAL, WANDA K · 2018 to 2022
$7.2M
Mentoring Research in Precision Medicine for Lung DiseaseK24HL137013 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PRESCOTT G WOODRUFF · 2017 to 2026
$1.2M
NHLBI NIH HHS HHSN268200900013CNHLBI NIH HHS HHSN268200900014CNHLBI NIH HHS HHSN268200900015CNHLBI NIH HHS HHSN268200900016CNHLBI NIH HHS HHSN268200900017CNHLBI NIH HHS HHSN268200900018CNHLBI NIH HHS HHSN268200900019CNHLBI NIH HHS HHSN268200900020CNHLBI NIH HHS K24 HL137013NHLBI NIH HHS U01 HL137880NHLBI NIH HHS U24 HL141762NIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

Background: Limited data are available regarding marijuana smoking's impact on the development or progression of chronic obstructive pulmonary disease (COPD) in middle-aged or older adults with a variable history of tobacco cigarette smoking. Methods: We divided ever-tobacco smoking participants in the SubPopulations and InteRmediate Outcomes In COPD Study (SPIROMICS) into 3 groups based on self-reported marijuana use: current, former, or never marijuana smokers (CMSs, FMSs or NMSs, respectively). Longitudinal data were analyzed in participants with ≥2 visits over a period of ≥52 weeks. Measurements: We compared CMSs, FMSs, and NMSs, and those with varying amounts of lifetime marijuana use. Mixed effects linear regression models were used to analyze changes in spirometry, symptoms, health status, and radiographic metrics; zero-inflated negative binomial models were used for exacerbation rates. All models were adjusted for age, sex, race, baseline tobacco smoking amount, and forced expiratory volume in 1 second (FEV Results: Most participants were followed for ≥4 years. Annual rates of change in FEV Conclusions: Among SPIROMICS participants with or without COPD, neither former nor current marijuana smoking of any lifetime amount was associated with evidence of COPD progression or its development. Because of our study's limitations, these findings underscore the need for further studies to better understand longer-term effects of marijuana smoking in COPD.

Indexed as

COPDExacerbationsHRCTMarijuanaSpirometry

Identifiers

PMID37199732
PMCPMC10484485
OpenAlexW4377007756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.