Evidence map›Paper›PMID 37199658›Full record

ArticleJournal of bacteriology2023

Manganese Acts as an Environmental Inhibitor of Pseudomonas aeruginosa Biofilm Development by Inducing Dispersion and Modulating c-di-GMP and Exopolysaccharide Production via RbdA.

Soyoung Park, Jozef Dingemans, Karin Sauer

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Biofilm dispersion byJournal of bacteriology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Soyoung ParkDepartment of Biological Sciences, Binghamton University, Binghamton, New York, USA.
Jozef DingemansDepartment of Biological Sciences, Binghamton University, Binghamton, New York, USA.
Karin SauerDepartment of Biological Sciences, Binghamton University, Binghamton, New York, USA.ORCID 0000-0002-1177-6328
Binghamton University · US

Funding

Role of PA4878 in biofilm antimicrobial resistanceR01AI080710 · NIAID · STATE UNIVERSITY OF NY,BINGHAMTON · PI LAU, GEE W, SAUER, KARIN · 2009 to 2020
$3.1M
Dispersion and the Biofilm Matrix of Pseudomonas aeruginosaR01AI150761 · NIAID · STATE UNIVERSITY OF NY,BINGHAMTON · PI MATTHEW R. PARSEK, Karin Sauer · 2021 to 2026
$2.8M
NIAID NIH HHS R01 AI080710NIAID NIH HHS R01 AI150761
6 · The paper itself

Abstract

The opportunistic human pathogen Pseudomonas aeruginosa causes chronic infections that involve multicellular aggregates called biofilms. Biofilm formation is modulated by the host environment and the presence of cues and/or signals, likely affecting the pool of the bacterial second messenger cyclic diguanylate monophosphate (c-di-GMP). The manganese ion Mn

Indexed as

ManganesePseudomonas aeruginosaBacterial ProteinsBiofilmsCyclic GMPGene Expression Regulation, BacterialHumansPolysaccharidesBacterial Proteinsbis(3',5')-cyclic diguanylic acidCyclic GMPManganesePolysaccharidesattachmentbiofilm formationbiofilm matrixbiofilmsDipAdispersiondiverse environmentexpolpoysaccharidesmanganeseP. aeruginosaPelphosphodiesterasesPslRbdASagS

Identifiers

PMID37199658
PMCPMC10294637
OpenAlexW4377012006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.