Evidence map›Paper›PMID 37199626›Full record

ArticleMicrobiology spectrum2023

OpaR Exerts a Dynamic Control over c-di-GMP Homeostasis and

David Zamorano-Sánchez, Jesús E Alejandre-Sixtos, Adilene Arredondo-Hernández, Raquel Martínez-Méndez

Abstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. LtrB inhibitsCurrent research in food science · 2026
    Article
  4. Article
  5. AphA-dependent c-di-GMP production inJournal of bacteriology · 2025
    Article
  6. CalR is an activator of biofilm formation inApplied and environmental microbiology · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David Zamorano-SánchezPrograma de Microbiología Genómica, Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, Mexico.ORCID 0000-0002-5580-7499
Jesús E Alejandre-SixtosPrograma de Microbiología Genómica, Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, Mexico.
Adilene Arredondo-HernándezPrograma de Microbiología Genómica, Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, Mexico.
Raquel Martínez-MéndezPrograma de Microbiología Genómica, Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The second messenger cyclic dimeric GMP (c-di-GMP) plays a central role in controlling decision-making processes that are vitally important for the environmental survival of the human pathogen Vibrio parahaemolyticus. The mechanisms by which c-di-GMP levels and biofilm formation are dynamically controlled in V. parahaemolyticus are poorly understood. Here, we report the involvement of OpaR in controlling c-di-GMP metabolism and its effects on the expression of the trigger phosphodiesterase (PDE) TpdA and the biofilm-matrix related gene

Indexed as

Vibrio parahaemolyticusBacterial ProteinsBiofilmsCyclic GMPDiethylstilbestrolGene Expression Regulation, BacterialHomeostasisHumansPhosphoric Diester HydrolasesBacterial Proteinsbis(3',5')-cyclic diguanylic acidCyclic GMPDiethylstilbestroldiethylstilbestrol monophosphatePhosphoric Diester Hydrolasesbiofilmsc-di-GMPgene-regulationsignal transductionVibrio parahaemolyticus

Identifiers

PMID37199626
PMCPMC10269520

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.