Evidence map›Paper›PMID 37199479›Full record

ArticleAdvanced healthcare materials2023

A Facile Crystallization Strategy to Turn Calcium Bisphosphonates into Novel Osteogenesis-Inducing Biomaterials.

Chen Zhuang, Guanglin Zhu, Yingjun Wang, Lin Wang, Xuetao Shi, Chuanbin Mao

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced healthcare materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Chen ZhuangSchool of Materials Science and Engineering, South China University of Technology, 510640, Guangzhou, P. R. China.
Guanglin ZhuSchool of Materials Science and Engineering, South China University of Technology, 510640, Guangzhou, P. R. China.
Yingjun WangNational Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, 510006, Guangzhou, P. R. China.
Lin WangNational Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, 510006, Guangzhou, P. R. China.
Xuetao ShiSchool of Materials Science and Engineering, South China University of Technology, 510640, Guangzhou, P. R. China.
Chuanbin MaoDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Sha Tin, Hong Kong SAR, China.ORCID 0000-0002-8142-3659
South China University of Technology · CNChinese University of Hong Kong · HKGuangzhou Regenerative Medicine and Health Guangdong Laboratory · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insoluble metal bisphosphonates (BPs) are considered an ideal alternative to the soluble counterparts in regenerative medicine due to their increased BP release profile, but still present undesired properties (e.g., low stability, uncontrolled degradation, and poor biocompatibility). Through a simple crystallization on a solid calcium hydroxyapatite (HA)-based substrate from a BP precursor solution in 30 days, a series of insoluble calcium BP (CaBP) crystals are developed. These crystals, including calcium alendronate (CaAln), calcium pamidronate (CaPam), calcium incadronate (CaInc), calcium risedronate (CaRis), calcium zoledronate (CaZol), and calcium di-minodronate (Ca(Min)

Indexed as

Biocompatible MaterialsOsteogenesisAnimalsBone RegenerationCalciumCell DifferentiationCrystallizationDiphosphonatesDurapatiteRabbitsBiocompatible MaterialsCalciumDiphosphonatesDurapatitebone regenerationcalcium bisphophonatecrystal morphologycrystal structuresdegradation

Identifiers

PMID37199479
PMCPMC11469325
OpenAlexW4377011003

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.