Evidence map›Paper›PMID 37199378›Full record

Trial reportCancer medicine2023

Adherence and contamination in a 1-year physical activity program in childhood cancer survivors: A report from the SURfit study.

Ruedi Jung, Simeon J Zürcher, Christina Schindera, Julia Braun, Wei Hai Deng, Nicolas X von der Weid, Corina S Rueegg, Susi Kriemler

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02730767 (Effects of a 1-year Partially Supervised Exercise Program in Childhood Cancer Survivors - a Randomized Controlled Trial), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02730767 nacompletednot on this map

Effects of a 1-year Partially Supervised Exercise Program in Childhood Cancer Survivors - a Randomized Controlled Trial

TypeinterventionalSponsorUniversity of ZurichRan2015 to 2019Enrolled151ConditionsLate-effects of Childhood CancerArmspartially supervised exercise intervention
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Ruedi JungEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.ORCID 0000-0001-9135-1495
Simeon J ZürcherCenter for Psychiatric Rehabilitation, University Hospital for Mental Health, University of Bern, Bern, Switzerland.ORCID 0000-0002-7759-747X
Christina SchinderaPediatric Oncology/Hematology, University Children's Hospital Basel, Basel, Switzerland.ORCID 0000-0002-4511-287X
Julia BraunEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.ORCID 0000-0001-8359-6177
Wei Hai DengOslo Centre for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway.ORCID 0000-0001-8194-9303
Nicolas X von der WeidPediatric Oncology/Hematology, University Children's Hospital Basel, Basel, Switzerland.ORCID 0000-0002-9555-3817
Corina S RueeggOslo Centre for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway.ORCID 0000-0003-3720-4659
Susi KriemlerEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-3384-7940
University of Zurich · CHOslo University Hospital · NOUniversity of Bern · CHUniversity Children’s Hospital Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMeeting intervention requirements is crucial in behavioral trials. We examined patterns and predictors of physical activity (PA) adherence and contamination in a 1-year individualized randomized controlled PA behavioral intervention in childhood cancer survivors (CCS).

methodsCCS aged ≥16 at enrolment, <16 at diagnosis, and ≥5 years in remission were identified from the Swiss Childhood Cancer Registry. We asked participants randomized to the intervention group to perform an additional ≥2.5 h of intense PA/week and controls to continue as usual. Adherence to the intervention was assessed by online diary (adherent if ≥2/3 of individual PA goal reached) and contamination for the control group by pre- and post-questionnaire including PA levels (contaminated if >60 min increase/week in PA). Predictors of adherence/contamination including quality of life (36-Item Short Form Survey) were assessed by questionnaire. We used logistic (control group) and mixed logistic regression models (exercise group) to estimate predictors of study adherence and contamination.

resultsOne hundred and forty-four survivors (30.4 ± 8.7 years old, 43% females) were included. Adherence was 48% (35/73) in the intervention group, while 17% (12/71) of controls contaminated group allocation. Predictors for PA adherence were female sex (OR 2.35, p = 0.03), higher physical (OR 1.34, p = 0.01) and mental quality of life (OR 1.37, p = 0.001), and week into the intervention (OR 0.98, p < 0.001). Clear differences in PA behavior of adherent and non-adherent participants were seen from week four. No significant predictors for contamination were found for controls.

conclusionAdherence to PA behavior interventions remain challenging in both groups. Further long-term trials should consider intense motivational support within the first month, more detailed data collection for the control group, adjustments to power calculations and other study designs to minimize non-adherence and contamination.

Indexed as

Cancer SurvivorsNeoplasmsAdultChildExerciseFemaleHumansMaleQuality of LifeSurveys and QuestionnairesYoung Adultadherencechildhood cancer survivorscontaminationexercisephysical activity

Identifiers

PMID37199378
PMCPMC10358195
OpenAlexW4377010877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.