Evidence map›Paper›PMID 37198900›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

Push and Fluff technique for optimization of clot integration with stent-retriever: An in vitro model.

Agostinho C Pinheiro, Raul G Nogueira, Ryan M Grandfield, Shao-Pow Lin, Aniel Q Majjhoo, Amin Nima Aghaebrahim, Michael G Abraham, Paul Mazaris, Justin A Singer, Alhamza R Al-Bayati and 3 more

Open access · greenAbstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 1 country.

Agostinho C PinheiroDepartment of Neurology, Marcus Stroke & Neuroscience Center, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0002-2496-9479
Raul G NogueiraUPMC Stroke Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Ryan M GrandfieldStryker Neurovascular, Freemont, CA, USA.
Shao-Pow LinPIH Health and LA Imaging and Interventional Consultants, Whittier, CA, USA.
Aniel Q MajjhooMcLaren Flint Hospital, Flint, MI and McLaren Macomb Hospital, Mount Clemens, MI, USA.
Amin Nima AghaebrahimBaptist Health, Jacksonville, FL, USA.
Michael G AbrahamDepartments of Neurology and Radiology, University of Kansas Medical Center, Kansas City, KS, USA.
Paul MazarisDepartment of Neurological Surgery, Spectrum Health, Michigan State University, Grand Rapids, MI, USA.
Justin A SingerDepartment of Neurological Surgery, Spectrum Health, Michigan State University, Grand Rapids, MI, USA.
Alhamza R Al-BayatiUPMC Stroke Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.ORCID 0000-0001-8103-1930
Leonard H VerheyDepartment of Neurological Surgery, Spectrum Health, Michigan State University, Grand Rapids, MI, USA.
Eugene LinMercy Health, St Vincent Medical Center, Toledo, OH, USA.
Diogo C HaussenDepartment of Neurology, Marcus Stroke & Neuroscience Center, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, GA, USA.
Spectrum Health · USGrady Memorial Hospital · USUniversity of Pittsburgh Medical Center · USBaptist Medical Center Jacksonville · USMcLaren Regional Medical Center · USMercy St. Vincent Medical Center · USPIH Health · USStryker (United States) · USUniversity of Kansas Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundFor stent-retriever (SR) thrombectomy, technical developments such as the Push and Fluff technique (PFT) appear to have a significant impact on procedural success. This study aimed to (1) quantify the enhancement in clot traction when using PFT as compared to the standard unsheathing technique (SUT) and (2) to evaluate the performance of PFT in new versus established users of the technique.MethodsOperators were divided between established PFT and SUT users. Each experiment was labeled according to the SR size, utilized technique, and operator experience. A three-dimensional-printed chamber with a clot simulant was used. After each retriever deployment, the SR wire was connected to a force gauge. Tension was applied by pulling the gauge until clot disengagement. The maximal force was recorded.ResultsA total of 167 experiments were performed. The median overall force to disengage the clot was 1.11 pounds for PFT and 0.70 pounds for SUT (an overall 59.1% increment with PFT; p < 0.001). The PFT effect was consistent across different retriever sizes (69% enhancement with the 3  ×  32mm device, 52% with the 4  ×  28mm, 65% with the 4  ×  41mm, 47% with the 6  ×  37mm). The ratio of tension required for clot disengagement with PFT versus SUT was comparable between physicians who were PFT versus SUT operators (1.595 [0.844] vs. 1.448 [1.021]; p: 0.424). The PFT/SUT traction ratio remained consistent from passes 1 to 4 of each technique in SUT users.ConclusionPFT led to reproduceable improvement in clot engagement with an average ∼60% increase in clot traction in this model and was found not to have a significant learning curve.

Indexed as

StentsThrombectomyThrombosisEquipment DesignHumansIn Vitro Techniquesin vitro modelmechanical thrombectomyPush and Fluffstroke

Identifiers

PMID37198900
PMCPMC12475377
OpenAlexW4377010821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.