Evidence map›Paper›PMID 37198392›Full record

ArticleScientific reports2023

Detection of dengue virus infection in children presenting with fever in Hawassa, southern Ethiopia.

Techalew Shimelis, Andargachew Mulu, Mesfin Mengesha, Aynalem Alemu, Adane Mihret, Birkneh Tilahun Tadesse, Adam W Bartlett, Fitsum W/Gebriel Belay, Gill Schierhout, Sabine Dittrich and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Mapping the Global Landscape of Dengue Fever Research: A Scientometric Analysis.Interdisciplinary perspectives on infectious diseases · 2025
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 6 countries.

Techalew ShimelisCollege of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia. techalew03@yahoo.com.
Andargachew MuluArmauer Hansen Research Institute, Addis Ababa, Ethiopia.
Mesfin MengeshaArmauer Hansen Research Institute, Addis Ababa, Ethiopia.
Aynalem AlemuArmauer Hansen Research Institute, Addis Ababa, Ethiopia.
Adane MihretArmauer Hansen Research Institute, Addis Ababa, Ethiopia.
Birkneh Tilahun TadesseCollege of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.
Adam W BartlettKirby Institute, University of New South Wales, Sydney, Australia.
Fitsum W/Gebriel BelayCollege of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.
Gill SchierhoutThe George Institute for Global Health, University of New South Wales, Sydney, Australia.
Sabine DittrichFoundation for Innovative New Diagnostics, Geneva, Switzerland.
John A CrumpCentre for International Health, University of Otago, Dunedin, New Zealand.
Susana Vaz NeryKirby Institute, University of New South Wales, Sydney, Australia.
John M KaldorKirby Institute, University of New South Wales, Sydney, Australia.
Armauer Hansen Research Institute · ETHawassa University · ETUNSW Sydney · AUThe George Institute for Global Health · AUUniversity of Otago · NZUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue fever is a mosquito-borne viral infection, with rising incidence globally. Eastern Ethiopia has had dengue fever outbreaks in recent years. However, the extent to which the infection contributes to hospital presentation among children with fever in southern Ethiopia is unknown. We examined 407 stored plasma samples collected to investigate the aetiology of fever in children aged at least 2 months and under 13 years presenting to the outpatient of the largest tertiary hospital in southern Ethiopia. We analyzed samples for dengue virus non-structural 1 antigen using enzyme-linked immunosorbent assay. The median (interquartile range) age of the 407 children examined was 20 (10-48) months, and 166 (40.8%) of the children were females. Of 407 samples analyzed, 9 (2.2%) were positive for dengue virus non-structural 1 antigen, of whom 2 were initially treated with antimalarial drugs despite having negative malaria microscopy, and 1 of the 8 patients had a persistent fever at the seventh day of follow-up time. The presence of active dengue virus infection in the study area highlights the need for studies at the community level as well as the integration of dengue diagnostics into fever-management strategies. Further research to characterize circulating strains is warranted.

Indexed as

DengueFlavivirusMalariaAnimalsChildEthiopiaFemaleFeverHumansMaleTertiary Care Centers

Identifiers

PMID37198392
PMCPMC10192357
OpenAlexW4377010472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.