ArticleScientific reports2023
Diagnostic role of aortic valve calcium scoring in various etiologies of aortic stenosis.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- A diagnostic pitfall of CT calcium scoring in paradoxical low-flow, low-gradient severe aortic stenosis with rheumatic morphology: a case report.European heart journal. Case reports · 2026Article
- Impact of Aortic Valve Calcium Burden on Paravalvular Leak Across Balloon-Expandable and Self-Expanding Valves: Insights from a Large TAVR Cohort.Journal of clinical medicine · 2026Article
- Aortic Valve Calcium Score Spectrum Identifies Bimodal Outcomes for Transcatheter Aortic Valve Implantation: Insights From the AMTRAC Registry.Journal of the American Heart Association · 2026Article
- Sex-Specific Coronary Artery Calcium Score Threshold Predictive of Obstructive Coronary Artery Disease.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- Ex Vivo Quantification of Calcification Stiffness in Aortic Stenosis: Biomechanical Data from Resected Human Valves.Annals of biomedical engineering · 2025Article
- Influence of Coronary Flow and Left Ventricular Outflow Tract Velocity on LDL Accumulation and Calcification in Aortic Valve Leaflets.Biomechanics (Basel, Switzerland) · 2025Article
- How to Manage Double Obstructions: Stories of Aortic and Mitral Stenosis.JACC. Case reports · 2025Article
- Prognostic and therapeutic implications of a low aortic valve calcium score in patients with low-gradient aortic stenosis.European heart journal. Cardiovascular Imaging · 2025Article
- Aortic Valve Calcium: A Narrative Review of its Role in the Assessment of Aortic Stenosis and as a Predictor of Post-transcatheter Aortic Valve Implantation Outcomes.Interventional cardiology (London, England) · 2025Review
- Aortic Valve Calcium Score: Applications in Clinical Practice and Scientific Research-A Narrative Review.Journal of clinical medicine · 2024Review
- Aortic Valve Calcium Score by Computed Tomography as an Adjunct to Echocardiographic Assessment-A Review of Clinical Utility and Applications.Journal of imaging · 2023Review
- Calcium Scoring to Classify Aortic Valve Stenosis Severity: What Is the Current Data?Current cardiology reports · 2023Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most of the studies about aortic valve calcium (AVC) score in aortic stenosis (AS) were based on degenerative or bicuspid AS but not rheumatic AS. We aimed to study the diagnostic accuracy of AVC score to determine severe AS in various etiologies. Adult patients diagnosed with mild to severe AS were enrolled. AVC score were identified from multi-detector computed tomography (MDCT) scan. The AVC score was highest in bicuspid AS (3211.9 (IQR (1100.0-4562.4) AU) compared to degenerative AS (1803.7 (IQR (1073.6-2550.6) AU)), and rheumatic AS (875.6 (IQR 453.3-1594.0) AU), p < 0.001. For the ROC curve to identify severe AS, the AVC score performed well in degenerative and bicuspid AS with the area under the ROC curve (AuROC) 0.834 (95% CI, 0.730, 0.938) in degenerative group; and 0.820 (95% CI, 0.687, 0.953) in bicuspid AS. Whereas AVC score had non-significant diagnostic accuracy with AuROC 0.667 (95% CI, 0.357, 0.976) for male and 0.60(95% CI, 0.243, 0.957) for female in rheumatic AS. The cut-off AVC score values to identify severe AS were AVCS > 2028.9AU (male) and > 1082.5AU (female) for degenerative AS, and > 2431.8AU (male) and > 1293.5AU (female) for bicuspid AS. In conclusions, AVC score is the accurate test for assessing severity in patients with degenerative and bicuspid AS but performs poorly in rheumatic AS group.
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