Evidence map›Paper›PMID 37197984›Full record

ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Connecting Connectomes to Physiology.

Alexander Borst, Christian Leibold

Abstract readReview
In one paragraph

Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Differential temporal filtering in the fly optic lobe.Journal of computational neuroscience · 2025
    Article
  2. Review
  3. Connectivity Matrix Seriation via Relaxation.PLoS computational biology · 2024
    Article
  4. New Challenges for Anatomists in the Era of Omics.Diagnostics (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alexander BorstMax-Planck Institute for Biological Intelligence, Department Circuits-Computation-Models, Martinsried, Germany.ORCID 0000-0001-5537-8973
Christian LeiboldFakultät für Biologie & Bernstein Center Freiburg, Albert-Ludwigs-Universität Freiburg, D-79104, Freiburg, Germany christian.leibold@biologie.uni-freiburg.de.ORCID 0000-0002-4859-8000

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the advent of volumetric EM techniques, large connectomic datasets are being created, providing neuroscience researchers with knowledge about the full connectivity of neural circuits under study. This allows for numerical simulation of detailed, biophysical models of each neuron participating in the circuit. However, these models typically include a large number of parameters, and insight into which of these are essential for circuit function is not readily obtained. Here, we review two mathematical strategies for gaining insight into connectomics data: linear dynamical systems analysis and matrix reordering techniques. Such analytical treatment can allow us to make predictions about time constants of information processing and functional subunits in large networks.

Indexed as

ConnectomeComputer SimulationNeuronsconnectomicsnetwork dynamicsneural circuits

Identifiers

PMID37197984
PMCPMC10198452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.