Evidence map›Paper›PMID 37197831›Full record

ArticleBMJ case reports2023

Dasatinib-associated follicular lymphoma in a patient with B-cell acute lymphoblastic leukaemia.

Katherine Ismei Zhou, Chenyu Lin, Jadee Lee Neff, Ahmed Galal

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Katherine Ismei ZhouDivision of Medical Oncology, Duke University Health System, Durham, North Carolina, USA.ORCID http://orcid.org/0000-0001-6442-0475
Chenyu LinDivision of Hematologic Malignancies & Cellular Therapy, Duke University Health System, Durham, North Carolina, USA.
Jadee Lee Neff *Department of Pathology, Duke University Health System, Durham, North Carolina, USA ahmed.galal@duke.edu jadee.neff@duke.edu.
Ahmed Galal *Division of Hematologic Malignancies & Cellular Therapy, Duke University Health System, Durham, North Carolina, USA ahmed.galal@duke.edu jadee.neff@duke.edu.
Duke University Health System · US

Funding

TRANSFUSION MEDICINE AND RELATED AREAST32HL007057 · NHLBI · DUKE UNIVERSITY · PI Gowthami M Arepally · 1985 to 2026
$10.6M
NHLBI NIH HHS T32 HL007057
6 · The paper itself

Abstract

The tyrosine kinase inhibitor dasatinib is approved for the treatment of chronic myeloid leukaemia and Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukaemia (ALL). Patients on dasatinib can rarely develop a form of benign reversible reactive lymphadenopathy termed follicular lymphoid hyperplasia (FLH). Here, we describe a patient with Ph+ ALL who developed follicular lymphoma (FL) after prolonged treatment with dasatinib and who had complete remission of FL after discontinuation of dasatinib. This case suggests that dasatinib-associated FLH could be a premalignant condition that can transform into FL. Moreover, withdrawal of dasatinib may be sufficient for remission of dasatinib-associated FL.

Indexed as

Leukemia, Myelogenous, Chronic, BCR-ABL PositiveLymphoma, FollicularPrecursor B-Cell Lymphoblastic Leukemia-LymphomaPrecursor Cell Lymphoblastic Leukemia-LymphomaDasatinibHumansPhiladelphia ChromosomeProtein Kinase InhibitorsDasatinibProtein Kinase InhibitorsDasatinibHaematology (incl blood transfusion)OncologyTyrosine Kinase Inhibitor

Identifiers

PMID37197831
PMCPMC10193045
OpenAlexW4376880378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.