Evidence map›Paper›PMID 37197799›Full record

ArticleBMJ mental health2023

Increasing the value of digital phenotyping through reducing missingness: a retrospective review and analysis of prior studies.

Danielle Currey, John Torous

Abstract read
In one paragraph

Article in BMJ mental health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Big data and psychiatry: advances, constraints and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
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  4. Big data research: the importance of the data-generating process and domain expertise.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
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  15. Observational
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  19. Unobtrusive inference of circadian rhythms from smartphone data.medRxiv : the preprint server for health sciences · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Danielle CurreyHarvard Medical School, Boston, Massachusetts, USA.
John TorousHarvard Medical School, Boston, Massachusetts, USA jtorous@bidmc.harvard.edu.ORCID 0000-0002-5362-7937

Funding

Wellcome Trust WT215843/Z/19/Z
6 · The paper itself

Abstract

backgroundDigital phenotyping methods present a scalable tool to realise the potential of personalised medicine. But underlying this potential is the need for digital phenotyping data to represent accurate and precise health measurements.

objectiveTo assess the impact of population, clinical, research and technological factors on the digital phenotyping data quality as measured by rates of missing digital phenotyping data.

methodsThis study analyses retrospective cohorts of mindLAMP smartphone application digital phenotyping studies run at Beth Israel Deaconess Medical Center between May 2019 and March 2022 involving 1178 participants (studies of college students, people with schizophrenia and people with depression/anxiety). With this large combined data set, we report on the impact of sampling frequency, active engagement with the application, phone type (Android vs Apple), gender and study protocol features on missingness/data quality.

findingsMissingness from sensors in digital phenotyping is related to active user engagement with the application. After 3 days of no engagement, there was a 19% decrease in average data coverage for both Global Positioning System and accelerometer. Data sets with high degrees of missingness can generate incorrect behavioural features that may lead to faulty clinical interpretations.

conclusionsDigital phenotyping data quality requires ongoing technical and protocol efforts to minimise missingness. Adding run-in periods, education with hands-on support and tools to easily monitor data coverage are all productive strategies studies can use today. CLINICAL IMPLICATIONS: While it is feasible to capture digital phenotyping data from diverse populations, clinicians should consider the degree of missingness in the data before using them for clinical decision-making.

Indexed as

MedicineMobile ApplicationsHumansRetrospective StudiesStudentsDepression & mood disordersSchizophrenia & psychotic disorders

Identifiers

PMID37197799
PMCPMC10231441

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.