Evidence map›Paper›PMID 37197736›Full record

ArticleNeuro-oncology advances

Diffuse leptomeningeal glioneuronal tumor in a child masquerading as an intramedullary spinal pilocytic astrocytoma.

Peter J Madsen, Madison L Hollawell, Mariarita Santi, Lea F Surrey, Arastoo Vossough, Brent A Orr, Christine Hill-Kayser, Alexander M Tucker, Phillip B Storm, Jessica B Foster

Open access · goldAbstract read
In one paragraph

Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Peter J MadsenDivision of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Madison L HollawellCenter for Data Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-5538-7295
Mariarita SantiDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Lea F SurreyDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Arastoo VossoughDepartment of Radiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Brent A OrrDepartment of Pathology, St. Jude Children's Hospital, Memphis, Tennessee, USA.
Christine Hill-KayserDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Alexander M TuckerDivision of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Phillip B StormDivision of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Jessica B FosterDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Children's Hospital of Philadelphia · USSt. Jude Children's Research Hospital · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse leptomeningeal glioneuronal tumor (DLGNT) occurs predominantly in children and is typically characterized by diffuse leptomeningeal lesions throughout the neuroaxis with focal segments of parenchymal involvement. Recent reports have identified cases without diffuse leptomeningeal involvement that retain classic glioneuronal features on histology. In this report, we present a case of a 4-year-old boy with a large cystic-solid intramedullary spinal cord lesion that on surgical biopsy revealed a biphasic astrocytic tumor with sparsely distributed eosinophilic granular bodies and Rosenthal fibers. Next-generation sequencing revealed a

Indexed as

diffuse leptomeningeal glioneuronal tumormethylationspinal tumor

Identifiers

PMID37197736
PMCPMC10184509
OpenAlexW4366452148

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.