ArticleOrthopedic reviews2023
Meniscal extrusion: risk factors and diagnostic tools to predict early osteoarthritis.
Article in Orthopedic reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Evaluating the diagnostic performance of MRI-based signs for identification of meniscus posterior root tears: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2026Pooled it
- Risk factors for high-grade pivot shift in patients with anterior cruciate ligament tears combined with lateral meniscus posterior root tears: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Osteoarthritis Development Following Meniscectomy vs. Meniscal Repair for Posterior Medial Meniscus Injuries: A Systematic Review.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Association between medial meniscal extrusion and knee structural progression in adults with symptomatic knee osteoarthritis - a prospective cohort study.Skeletal radiology · 2025Trial
- Acute rather than insidious symptom onset is associated with better postoperative outcomes after transtibial pull-out repair for medial meniscus posterior root tears.Journal of experimental orthopaedics · 2026Article
- Combined Arthroscopic Medial Meniscal Root Repair and Centralization Using All-Suture Anchors Without a Posteromedial Portal.Arthroscopy techniques · 2026Article
- Meniscal extrusion increases with age: Decade-specific magnetic resonance imaging reference values.Journal of experimental orthopaedics · 2026Article
- Biomechanical impact of discoid lateral meniscus and partial meniscectomy in the pediatric knee: a finite element study.Medical & biological engineering & computing · 2026Article
- Activated platelet rich plasma modulates the proliferation, apoptosis and matrix synthesis driven by growth factors in osteoarthritic chondrocytes: anFrontiers in bioengineering and biotechnology · 2026Article
- Article
- Quantitative meniscus imaging and analysis: A narrative review.Osteoarthritis imaging · 2025Article
- Simplified Centralization Technique With Dual-Tunnel Meniscal Root Repair.Arthroscopy techniques · 2025Article
- Identification of Genes Linked to Meniscal Degeneration in Osteoarthritis: An In Silico Analysis.International journal of molecular sciences · 2025Article
- Receptor activator of nuclear factor-kappa B ligand-derived microglia healing peptide 1-AcN inhibits osteoarthritis progression in mice.Arthritis research & therapy · 2025Article
- A review of finite element modeling and surgical simulation of meniscal tear in knee joint: progress and challenges.Frontiers in medicine · 2025Review
- Subchondral insufficiency fracture of the knee: progress in the pathogenesis and treatment.Frontiers in surgery · 2025Review
- Association between meniscal extrusion and disease severity in knee osteoarthritis: a retrospective case-control study.BMC musculoskeletal disorders · 2024Article
- Enhanced Pain Reduction at Different Stages of Knee Osteoarthritis via Repeated Injections of Hyaluronic Acid with Niacinamide: A Comparative Study.Journal of clinical medicine · 2024Article
- LncRNA-mediated cartilage homeostasis in osteoarthritis: a narrative review.Frontiers in medicine · 2024Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Meniscal extrusion (ME) is strongly correlated with cartilage wear and osteoarthritis (OA), be-cause of the altered kinematic and the decreased contact area between the tibia and femur. The aim of this narrative review is to analyze the process of ME, focusing on the possible causes, and to evaluate the correlation between ME and knee OA, in order to provide early diagnosis and treatments. Studies written in English that analyzed the causes of ME, provided indications re-garding diagnosis and treatment, and evaluated the relation between ME and early OA were in-cluded. Injuries, degeneration of the meniscal substance and meniscus root tears are associated with significantly increased ME. An extruded meniscus could be a manifestation of other pa-thologies such as disruption of coronary ligaments, cartilage loss, knee malalignment, ligament injuries, or OA. ME is strongly associated with osteoarthritis features, particularly with bone marrow lesion and cartilage damage. Magnetic resonance imaging represents the gold standard for the detection of ME. The severity of the medial meniscus extrusion may also affect healing af-ter repair, and meniscus extrusion is not completely reduced by meniscus posterior root tear re-pair. In this study, we proved that ME represents an important risk factor for early knee OA. We provided alternative theories of ME, such as meniscal fibers injury first and "dynamic extrusion of the menisci". The phenomenon of aging has been described as a new concept in the etiology of ME. Finally, we stated all the main techniques and characteristics of the diagnostic process, as well as the current knowledge in the therapeutic field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.