Evidence map›Paper›PMID 37197501›Full record

ArticleJournal of thoracic disease2023

Efficiency and toxicity of nab-paclitaxel and camrelizumab in the second or above line treatment of advanced non-small cell lung cancer: a retrospective cohort study.

Chen Yin, Guo-Rong Zou, Yan He, Juan Li, Hao-Wen Yan, Zhen Su, Xiao-Long Cao, Xiao-Bing Li

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Chen Yin *Department of Oncology, Panyu Central Hospital, Cancer Institute of Panyu, Guangzhou, China.
Guo-Rong Zou *Department of Oncology, Panyu Central Hospital, Cancer Institute of Panyu, Guangzhou, China.
Yan HeDepartment of Oncology, Panyu Central Hospital, Cancer Institute of Panyu, Guangzhou, China.
Juan LiDepartment of Oncology, Panyu Central Hospital, Cancer Institute of Panyu, Guangzhou, China.
Hao-Wen YanDepartment of Oncology, Panyu Central Hospital, Cancer Institute of Panyu, Guangzhou, China.
Zhen SuDepartment of Oncology, Panyu Central Hospital, Cancer Institute of Panyu, Guangzhou, China.
Xiao-Long CaoDepartment of Oncology, Panyu Central Hospital, Cancer Institute of Panyu, Guangzhou, China.
Xiao-Bing LiThe First Department of Thoracic Oncology, Hubei Cancer Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Panyu District Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Paclitaxel-based chemotherapy represented by nanoparticle albumin-bound paclitaxel (nab-ptx) combined with programmed cell death protein 1 (PD-1)/programmed death ligand 1 (PD-L1) inhibitors has become the standard model for the 1 Methods: We retrospectively collected the date of these advanced NSCLC patients who accept the combination treatment of PD-1/PD-L1 inhibitor and nab-ptx in the 2 Results: A total of 53 patients were enrolled in this study. The preliminary results indicated that the ORR of the combination of camrelizumab and nab-ptx was about 36% in the 2 Conclusions: The combination of nab-ptx and camrelizumab shows promising efficiency and lower toxicities for advanced NSCLC in the 2nd or above line treatment. The mechanism of action may be related to depleting Treg ratio; such a regimen may have the potential to become an effective treatment approach for NSCLC. However, due to the limitation of sample size, the real value of this regimen needs to be further confirmed in the future.

Indexed as

drug combinationNon-small cell lung cancer (NSCLC)programmed cell death protein 1/programmed death ligand 1 inhibitors (PD-1/PD-L1 inhibitors)

Identifiers

PMID37197501
PMCPMC10183515
OpenAlexW4367031758

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.