Evidence map›Paper›PMID 37197486›Full record

ArticleJournal of thoracic disease2023

Comprehensive bioinformatics analysis on exportins in lung adenocarcinoma and lung squamous cell carcinoma.

Meini Pan, Peng Huang, Linmao Li, Peng Lei, Lini Fang, Lifeng Zhao, Yepeng Li, Shiqing Huang, Weigui Luo

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Meini Pan *Department of Oncology, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Peng Huang *Department of Oncology, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Linmao Li *Department of Oncology, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Peng LeiDepartment of Radiology, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Lini FangDepartment of Oncology, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Lifeng ZhaoDepartment of Oncology, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Yepeng LiDepartment of Oncology, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Shiqing HuangDepartment of Oncology, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Weigui LuoDepartment of Respiratory and Critical Care, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Affiliated Hospital of Youjiang Medical University for Nationalities · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lung cancer is one of the most common malignant tumors in the world. Exportins are closely associated with the cellular activity and disease progression in a variety of different tumors. However, the expression level, genetic variation, immune infiltration, and biological function of different exportins in lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC), as well as their relationship with the prognosis of patients with LUAD and LUSC have not been fully clarified. Methods: To analyze the differential expression, prognostic value, genetic variation, biological function, and immune cell infiltration of exportins in patients with LUAD and LUSC, the ONCOMINE; UALCAN; Human Protein Atlas (HPA); Kaplan-Meier plotter; cBioPortal; Search Tool for the Retrieval of Interacting Genes/Proteins (STRING); Database for Annotation, Visualization, and Integrated Discovery (DAVID); Tumor Immune Estimation Resource (TIMER); and LinkedOmics databases were used in this study. Results: The transcriptional and protein expression levels of Conclusions: Our study provides novel insights into the selection of prognostic biomarkers of exportins in LUAD and LUSC.

Indexed as

Bioinformatics analysisbiomarkersexportinslung cancerprognostic value

Identifiers

PMID37197486
PMCPMC10183495
OpenAlexW4366968065

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.