Evidence map›Paper›PMID 37197445›Full record

ArticleInternational statistical review = Revue internationale de statistique2021

A Review of Spatial Causal Inference Methods for Environmental and Epidemiological Applications.

Brian J Reich, Shu Yang, Yawen Guan, Andrew B Giffin, Matthew J Miller, Ana Rappold

Abstract read
In one paragraph

Article in International statistical review = Revue internationale de statistique, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Article
  3. Modelling spatial heterogeneity in exposure buffers and risk: a hierarchical Bayesian approach.Journal of the Royal Statistical Society. Series C, Applied statistics · 2026
    Article
  4. Article
  5. Impacts of Social Environments on Neighborhood Depression Incidence: Fully Accounting for Spatial Effects.International journal of environmental research and public health · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. A research agenda for GIScience in a time of disruptions.International journal of geographical information science : IJGIS · 2025
    Article
  15. Article
  16. Estimating spatially varying health effects of wildland fire smoke using mobile health data.Journal of the Royal Statistical Society. Series C, Applied statistics · 2024
    Article
  17. Review
  18. Review
  19. Article
  20. Alleviating spatial confounding in frailty models.Biostatistics (Oxford, England) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brian J ReichDepartment of Statistics, North Carolina State University, Raleigh, NC 27695, USA.ORCID 0000-0002-5473-120X
Shu YangDepartment of Statistics, North Carolina State University, Raleigh, NC 27695, USA.ORCID 0000-0001-7703-707X
Yawen GuanDepartment of Statistics, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.
Andrew B GiffinDepartment of Statistics, North Carolina State University, Raleigh, NC 27695, USA.
Matthew J MillerDepartment of Statistics, North Carolina State University, Raleigh, NC 27695, USA.ORCID 0000-0002-7303-9454
Ana RappoldUS Environmental Protection Agency, Research Triangle Park, NC 27709, USA.

Funding

Data Integration Methods for Environmental Exposures with Applications to Air Pollution and Asthma MorbidityR01ES027892 · NIEHS · EMORY UNIVERSITY · PI CHANG, HOWARD H · 2017 to 2021
$2.7M
Spatial Causal Inference for Wildland Fire Smoke Effects on Air Pollution and HealthR01ES031651 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI REICH, BRIAN J., YANG, SHU · 2020 to 2024
$1.2M
NIEHS NIH HHS R01 ES027892NIEHS NIH HHS R01 ES031651
6 · The paper itself

Abstract

The scientific rigor and computational methods of causal inference have had great impacts on many disciplines but have only recently begun to take hold in spatial applications. Spatial causal inference poses analytic challenges due to complex correlation structures and interference between the treatment at one location and the outcomes at others. In this paper, we review the current literature on spatial causal inference and identify areas of future work. We first discuss methods that exploit spatial structure to account for unmeasured confounding variables. We then discuss causal analysis in the presence of spatial interference including several common assumptions used to reduce the complexity of the interference patterns under consideration. These methods are extended to the spatiotemporal case where we compare and contrast the potential outcomes framework with Granger causality and to geostatistical analyses involving spatial random fields of treatments and responses. The methods are introduced in the context of observational environmental and epidemiological studies and are compared using both a simulation study and analysis of the effect of ambient air pollution on COVID-19 mortality rate. Code to implement many of the methods using the popular Bayesian software OpenBUGS is provided.

Indexed as

interferencepotential outcomespropensity scoresspatial confoundingspillover

Identifiers

PMID37197445
PMCPMC10187770

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.