Evidence map›Paper›PMID 37196677›Full record

ArticleNature2023

EMC chaperone-Ca

Zhou Chen, Abhisek Mondal, Fayal Abderemane-Ali, Seil Jang, Sangeeta Niranjan, José L Montaño, Balyn W Zaro, Daniel L Minor

Open access · greenAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
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  5. Review
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  8. Article
  9. Review
  10. Article
  11. Article
  12. SARS-CoV-2 membrane protein biogenesis.bioRxiv : the preprint server for biology · 2026
    Article
  13. Chemical tuning reveals a cation-π gating bridge between the voltage-sensor and pore domains in the KProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  14. Article
  15. Article
  16. Brain communications · 2026
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Zhou ChenCardiovascular Research Institute, University of California, San Francisco, CA, USA.ORCID 0000-0002-4426-2497
Abhisek MondalCardiovascular Research Institute, University of California, San Francisco, CA, USA.
Fayal Abderemane-AliCardiovascular Research Institute, University of California, San Francisco, CA, USA.
Seil JangCardiovascular Research Institute, University of California, San Francisco, CA, USA.
Sangeeta NiranjanCardiovascular Research Institute, University of California, San Francisco, CA, USA.
José L MontañoDepartment of Pharmaceutical Chemistry, University of California, San Francisco, CA, USA.
Balyn W ZaroCardiovascular Research Institute, University of California, San Francisco, CA, USA.ORCID 0000-0002-8938-9889
Daniel L MinorCardiovascular Research Institute, University of California, San Francisco, CA, USA. daniel.minor@ucsf.edu.ORCID 0000-0002-5998-4214
University of California, San Francisco · USQB3 · USUniversity of California, Los Angeles · US

Funding

The Stanford-SLAC CryoEM Center supplementU24GM129541 · NIGMS · STANFORD UNIVERSITY · PI CHIU, WAH, HEDMAN, BRITT · 2018 to 2023
$54.8M
Structure and function of voltage-gated calcium channelsR01HL080050 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DANIEL L MINOR · 2005 to 2026
$9.8M
Structural Studies of Ion Channel Assembly and Signaling ComplexesR01DC007664 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DANIEL L MINOR · 2005 to 2026
$8.2M
Research Training in Chemistry and Chemical BiologyT32GM145460 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jason E Gestwicki · 2022 to 2026
$3.1M
Glacios™ Cryo Transmission Electron Microscope with 200 kV XFEG opticsS10OD026881 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHENG, YIFAN · 2019 to 2019
$1.8M
NHLBI NIH HHS R01 HL080050NIDCD NIH HHS R01 DC007664NIGMS NIH HHS T32 GM145460NIGMS NIH HHS U24 GM129541NIH HHS S10 OD026881
6 · The paper itself

Abstract

Voltage-gated ion channels (VGICs) comprise multiple structural units, the assembly of which is required for function

Indexed as

Calcium Channels, L-TypeEndoplasmic ReticulumMembrane ProteinsBinding SitesBrainCalcium ChannelsCryoelectron MicroscopyGabapentinHumansMyocardiumCACNA2D1 protein, humanCACNB3 protein, humanCalcium ChannelsCalcium Channels, L-TypeGabapentinL-type calcium channel alpha(1C)Membrane Proteins

Identifiers

PMID37196677
PMCPMC10896479
OpenAlexW4376878571

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.