Evidence map›Paper›PMID 37196406›Full record

ArticleGeneral hospital psychiatry

The association between preconception cannabis use and depression and anxiety during pregnancy.

Qian Liya Leng, Jamie O Lo, Shauna Rakshe, Andrea D Hildebrand, Olivia J Doyle, Kristen Mackiewicz Seghete, Alice Graham

Open access · greenAbstract read
In one paragraph

Article in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qian Liya LengCenter for Veteran Involvement in Care, VA Portland Healthcare System, Portland, OR, USA. Electronic address: qian.leng1@va.gov.
Jamie O LoDepartment of Obstetrics and Gynecology, Oregon Health & Science University; Portland, OR, USA.
Shauna RaksheKnight Cancer Institute Biostatistics Shared Resource and OHSU-PSU School of Public Health, Oregon Health & Science University, Portland, OR, USA.
Andrea D HildebrandBiostatistics & Design Program, OHSU/PSU School of Public Health, Oregon Health & Science University, Portland, OR, USA.
Olivia J DoyleDepartment of Psychiatry, Oregon Health & Science University, Portland, OR, USA.
Kristen Mackiewicz SegheteDepartment of Psychiatry, Oregon Health & Science University, Portland, OR, USA.
Alice GrahamDepartment of Psychiatry, Oregon Health & Science University, Portland, OR, USA.
Oregon Health & Science University · USVA Portland Health Care System · US

Funding

The Transgenerational Influence of Discrimination on Mental HealthU01DA055363 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Alice M Graham, Elinor L. Sullivan · 2021 to 2026
$8.8M
LINKS BETWEEN MATERNAL PSYCHOLOGICAL STRESS AND INFLAMMATION DURING PREGNANCY AND POTENTIAL FOR PREVENTIVE INTERVENTION: Supplement to R00MH111805R00MH111805 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI GRAHAM, ALICE M · 2018 to 2020
$934k
Mechanisms of Action of MBCT-PD: A Pilot StudyR21AT010292 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI MACKIEWICZ SEGHETE, KRISTEN L · 2018 to 2019
$424k
NCCIH NIH HHS R21 AT010292NIDA NIH HHS U01 DA055363NIMH NIH HHS R00 MH111805
6 · The paper itself

Abstract

objectiveCannabis use among individuals of reproductive age has increased with cannabis legalization and heightened stress during the COVID-19 pandemic. Our study provides data on preconception cannabis use and cannabis use disorder (CUD) during the pandemic and models the association between preconception cannabis use and depression and anxiety during pregnancy.

methodsData on substance use and depression and anxiety symptoms were collected from questionnaires and the Structured Clinical Interview for DSM-5 (SCID-5) from pregnant individuals in Oregon in 2019-2022. Linear regression was used to model the association between the frequency of preconception cannabis use and scores on the Center for Epidemiological Studies of Depression-Revised (CESD-R) and Beck Anxiety Inventory (BAI).

resultsThe prevalence of preconception cannabis use was 27.8% among 227 study participants. CUD was diagnosed in 19% of cannabis users, or 5.3% of the overall sample. Daily cannabis use, compared to rare/never use, was associated with increases in CESD-R (β = 6.22, p 0.029) and BAI (β = 4.71, p 0.045) scores.

conclusionsCannabis use and CUD are common among individuals of reproductive age. Given the association between preconception cannabis use and depression and anxiety during pregnancy, more attention is needed on screening and counseling of cannabis use among people of reproductive age.

Indexed as

CannabisCOVID-19Marijuana AbuseSubstance-Related DisordersAnxietyDepressionFemaleHumansPandemicsPregnancyCannabisMarijuanaMaternal mental healthPerinatal depressionPreconceptionSubstance use

Identifiers

PMID37196406
PMCPMC10428863
OpenAlexW4372232675

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.