Evidence map›Paper›PMID 37195598›Full record

ReviewCurrent atherosclerosis reports2023

Coronary Artery Disease Risk Prediction in Young Adults: How Can We Overcome the Dominant Effect of Age?

Seyedmohammad Saadatagah, Mini G Varughese, Vijay Nambi

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06362278 (A Multi-omics Study of Patients With Premature Coronary Artery Disease in the Absence of Common Risk Factors), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06362278 unknown statusnot on this mapstarted 2024, after this paper: background citation

A Multi-omics Study of Patients With Premature Coronary Artery Disease in the Absence of Common Risk Factors

TypeobservationalSponsorThe First Affiliated Hospital with Nanjing Medical UniversityRan2024 to 2025Enrolled160ConditionsCoronary Artery DiseaseArmsmulti-omics studies
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Seyedmohammad SaadatagahDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Mini G VarugheseSection of Cardiology, Department of Medicine, Baylor College of Medicine, 1 Baylor Plaza, 521D, MS 285, Houston, Texas, 77030, USA.
Vijay NambiSection of Cardiology, Department of Medicine, Baylor College of Medicine, 1 Baylor Plaza, 521D, MS 285, Houston, Texas, 77030, USA. vnambi@bcm.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewWe review the limitations of current approaches for predicting Coronary Artery Disease (CAD) in young adults and explore the alternative approaches identify high-risk individuals in this population. RECENT

findingsAtherosclerosis begins in childhood, and young individuals with genetic predisposition and individuals with early exposure to traditional and non-traditional risk factors have an increased lifetime risk of CAD. However, most risk prediction models have been developed and validated in middle and older age groups and focus on short-term risk. Therefore, alternative approaches are needed in younger individuals. Genetic scores, biomarkers, imaging studies, and multi-omics data all have the potential to be used and help identify high-risk individuals.

Indexed as

AtherosclerosisCoronary Artery DiseaseGenetic Predisposition to DiseaseHumansRisk FactorsYoung AdultBiomarkersCardiovascular disease in young ageMultiomics dataPolygenic risk scoreRisk predictionTraditional and non-traditional risk factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.