Trial reportIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2023
Comparison of the efficacies of triple, quadruple and sequential antibiotic therapy in eradicating Helicobacter pylori infection: A randomized controlled trial.
Trial report in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Mastic gum as an adjunct to bismuth quadruple therapy for Helicobacter pylori eradication.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- Comparative Efficacy of Triple Versus Quadruple Therapy for the Eradication ofJGH open : an open access journal of gastroenterology and hepatology · 2025Review
- Burden of Helicobacter pylori in Duodenal Ulcer Disease: Evidence From a Tertiary Hospital in Chennai, India.Cureus · 2025Article
- Enhanced urease inhibitory activity of quercetin via conjugation with silver nanoparticles: synthesis, characterization, and DFT study.Scientific reports · 2025Article
- Article
- Utility of commercially available triple drug regimen kits and addition of Lactobacillus reuteri in Helicobacter pylori eradication.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024Article
- Enduring Dilemmas in Gastroenterology.Diagnostics (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimThere is regional variation in the eradication rates of Helicobacter pylori (H. pylori) regimens depending on the local antibiotic resistance patterns. The aim of this study was to compare the efficacies of triple, quadruple and sequential antibiotic therapy in eradicating H. pylori infection.
methodsA total of 296 H. pylori-positive patients were randomized to receive one of the three regimens (triple, quadruple or sequential antibiotic therapy) and eradication rate was assessed by H. pylori stool antigen test.
resultsThe eradication rates of standard triple therapy, sequential therapy and quadruple therapy were 93%, 92.9% and 96.4%, respectively (p = 0.57).
conclusionFourteen days of standard triple therapy, 14 days of bismuth-based quadruple therapy and 10 days of sequential therapy are equally efficacious in eradicating H. pylori and all regimens have optimum H. pylori eradication rates.
trial registrationClinicalTrials.gov Identifier: CTRI/2020/04/024929.
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Registered trials
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