Evidence map›Paper›PMID 37195536›Full record

ArticleAdvances in experimental medicine and biology2023

Clinical Translation of Engineered Pulmonary Vascular Models.

Yifan Yuan

Abstract read
In one paragraph

Article in Advances in experimental medicine and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Yifan YuanDepartment of Medicine (Pulmonary), Department of Anesthesiology, Yale University, New Haven, CT, USA. yifan.yuan@yale.edu.

Funding

Reconstructing native soluble cues in vascularized whole lung scaffoldsR00HL159261 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI YUAN, YIFAN · 2023 to 2025
$747k
Reconstructing native soluble cues in vascularized whole lung scaffoldsK99HL159261 · NHLBI · YALE UNIVERSITY · PI YUAN, YIFAN · 2022 to 2023
$245k
NHLBI NIH HHS K99 HL159261NHLBI NIH HHS R00 HL159261
6 · The paper itself

Abstract

Diseases in pulmonary vasculature remain a major cause of morbidity and mortality worldwide. Numerous pre-clinical animal models were developed to understand lung vasculature during diseases and development. However, these systems are typically limited in their ability to represent human pathophysiology for the study of disease and drug mechanisms. In recent years, a growing number of studies have focused on developing in vitro experimental platforms that mimic human tissues/organs. In this chapter, we discuss the key components involved in developing engineered pulmonary vascular modeling systems and provide perspectives on ways to improve the translational potential of existing models.

Indexed as

LungTissue EngineeringAnimalsHumansModels, BiologicalCell-cell crosstalkCyclic stretchECMOrgan chipsOrganoidsPulmonary vasculatureShear stress

Identifiers

PMID37195536
PMCPMC13036811

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.