Evidence map›Paper›PMID 37195509›Full record

ArticleProbiotics and antimicrobial proteins2024

Impact of Habitual Yogurt Intake in Mother-Child Dyads on Incidence of Childhood Otitis Media: The Japan Environment and Children's Study (JECS).

Masahiro Tsuchiya, Shinobu Tsuchiya, Haruki Momma, Ryoukichi Ikeda, Jun Suzuki, Ryoichi Nagatomi, Nobuo Yaegashi, Takahiro Arima, Kaoru Igarashi, Japan Environment and Children’s Study Group

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Article in Probiotics and antimicrobial proteins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Masahiro TsuchiyaDepartment of Nursing, Tohoku Fukushi University, Sendai, Japan. tsuchiya-thk@umin.ac.jp.
Shinobu TsuchiyaDepartment of Orthodontics and Speech Therapy for Craniofacial Anomalies, Tohoku University Hospital, Sendai, Japan.
Haruki MommaDepartment of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, Japan.
Ryoukichi IkedaDepartment of Otolaryngology - Head and Neck Surgery, Iwate Medical School of University, Morioka, Japan.
Jun SuzukiDepartment of Otolaryngology - Head and Neck Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Ryoichi NagatomiDepartment of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, Japan.
Nobuo YaegashiDepartment of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Takahiro ArimaDepartment of Informative Genetics, Environment and Genome Research Center, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kaoru IgarashiDepartment of Orthodontics and Speech Therapy for Craniofacial Anomalies, Tohoku University Hospital, Sendai, Japan.
Japan Environment and Children’s Study Group
Tohoku University · JPTohoku University Hospital · JPIwate Medical University · JPTohoku Fukushi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Otitis media, one of the most common childhood diseases, is characterized by inflammation or infection of the middle ear. Due to their ease of access, daily probiotics are recommended for the prevention of early childhood otitis media. This study aimed to assess the impact of probiotics on the incidence of otitis media using a dataset (n = 95,380) from the Japan Environment and Children's Study, a nationwide birth cohort study. After multiple imputations, the association between the incidence of otitis media in early childhood and the daily frequency of yogurt intake in children and mothers was examined using a generalized linear model after adjusting for several confounders. Repeated incidence of otitis media during the 2 years after birth was found in 14,874 participants (15.6%). Based on participants with the lowest frequency of yogurt intake ("almost never") as the reference group, risk ratios for otitis media incidence decreased with higher frequencies of yogurt intake in children at one year of age, but also independently in mothers during pregnancy. The lowest risk ratio (95% confidence interval) for otitis media incidence at six months of age was observed with the most frequent yogurt intake (once/day or more) (0.54 [0.46-0.63]). Additionally, although a similar association was observed in the subgroup of those with cleft lip and/or palate (CL/P), a high-risk group for severe recurrent otitis media, no statistical significance was observed. Thus, increased regular yogurt intake in both children and mothers was associated with a decrease of otitis media during early childhood.

Indexed as

Otitis MediaYogurtAdultBirth CohortChild, PreschoolFemaleHumansIncidenceInfantJapanMaleMothersPregnancyProbioticsCleft lips and palateNationwide birth cohortOtitis mediaProbiotics

Identifiers

PMID37195509
OpenAlexW4376871762

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.