ReviewPlant cell reports2023
Role of F-box E3-ubiquitin ligases in plant development and stress responses.
Review in Plant cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 51 citations in OpenAlex.
- E3 ubiquitin ligases in plant defense: mechanisms and prospects for resistance breeding.Science China. Life sciences · 2026Review
- Evolution and functional characterization of the MdSKP8 gene as a conserved hub integrating hormone and antioxidant pathways for salt tolerance in apple.Plant cell reports · 2026Article
- Genome-wide dissection ofHorticulture research · 2026Article
- TheAntioxidants (Basel, Switzerland) · 2026Article
- Genome-wide phylogenetic analysis and expression profiling of F-box gene family in Verbena bonariensis under cold stress.BMC plant biology · 2026Article
- Article
- Integrating multiomic resources and gene expression studies to identify candidates for engineering climate-resilientFrontiers in plant science · 2026Review
- Candidate genes for anthracnose resistance in Senegalese sorghum: a machine learning-based exploration.Functional & integrative genomics · 2025Article
- OsHsp20-25, a small heat shock protein, from long-lived mRNA regulates seed size and germination rate in rice.Planta · 2025Article
- Mapping stress memory: genetic and epigenetic insights into combined drought and heat tolerance in barley.Plant cell reports · 2025Article
- Genome-Wide Identification and Expression Analysis of the YTH Domain-Containing Protein Gene Family inInternational journal of molecular sciences · 2025Article
- Noncoding elements in wheat defence response to fusarium head blight.Scientific reports · 2025Article
- Physiological and Transcriptional Responses of Sesame (International journal of molecular sciences · 2025Article
- The Role of E3 Ubiquitin Ligase GeneInternational journal of molecular sciences · 2025Review
- Genome-Wide Identification and Functional Characterization ofInternational journal of molecular sciences · 2025Article
- Molecular Functional and Transcriptome Analysis ofPlants (Basel, Switzerland) · 2024Article
- Identification and analysis of drought-responsive F-box genes in upland rice and involvement of OsFBX148 in ABA response and ROS accumulation.BMC plant biology · 2024Article
- Cullin-Conciliated Regulation of Plant Immune Responses: Implications for Sustainable Crop Protection.Plants (Basel, Switzerland) · 2024Review
- A Bacterial Platform for Studying Ubiquitination Cascades Anchored by SCF-Type E3 Ubiquitin Ligases.Biomolecules · 2024Article
- The lowdown on breakdown: Open questions in plant proteolysis.The Plant cell · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
key messageF-box E3-ubiquitin ligases regulate critical biological processes in plant development and stress responses. Future research could elucidate why and how plants have acquired a large number of F-box genes. The ubiquitin-proteasome system (UPS) is a predominant regulatory mechanism employed by plants to maintain the protein turnover in the cells and involves the interplay of three classes of enzymes, E1 (ubiquitin-activating), E2 (ubiquitin-conjugating), and E3 ligases. The diverse and most prominent protein family among eukaryotes, F-box proteins, are a vital component of the multi-subunit SCF (Skp1-Cullin 1-F-box) complex among E3 ligases. Several F-box proteins with multifarious functions in different plant systems have evolved rapidly over time within closely related species, but only a small part has been characterized. We need to advance our understanding of substrate-recognition regulation and the involvement of F-box proteins in biological processes and environmental adaptation. This review presents a background of E3 ligases with particular emphasis on the F-box proteins, their structural assembly, and their mechanism of action during substrate recognition. We discuss how the F-box proteins regulate and participate in the signaling mechanisms of plant development and environmental responses. We highlight an urgent need for research on the molecular basis of the F-box E3-ubiquitin ligases in plant physiology, systems biology, and biotechnology. Further, the developments and outlooks of the potential technologies targeting the E3-ubiquitin ligases for developing crop improvement strategies have been discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.