Evidence map›Paper›PMID 37195493›Full record

ArticleResearch on child and adolescent psychopathology2023

Associations Between Early Life Adversity and Youth Psychobiological Outcomes: Dimensional and Person-Centered Approaches.

Michaela Sisitsky, Megan Hare, Karissa DiMarzio, Adriana Gallat, Loreen Magariño, Justin Parent

Abstract read
In one paragraph

Article in Research on child and adolescent psychopathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Research Review: Assessment of early-life adversity and trauma - cumulative risk and dimensional approaches.Journal of child psychology and psychiatry, and allied disciplines · 2025
    Review
  4. Article
  5. The Impact of Early Life Adversity on Peripubertal Accelerated Epigenetic Aging and Psychopathology.Journal of the American Academy of Child and Adolescent Psychiatry · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michaela SisitskyCenter for Children and Families, Florida International University, Miami, USA. msisitsk@fiu.edu.ORCID 0000-0001-7668-5470
Megan HareCenter for Children and Families, Florida International University, Miami, USA.
Karissa DiMarzioCenter for Children and Families, Florida International University, Miami, USA.
Adriana GallatCenter for Children and Families, Florida International University, Miami, USA.
Loreen MagariñoCenter for Children and Families, Florida International University, Miami, USA.
Justin ParentCenter for Children and Families, Florida International University, Miami, USA.

Funding

NICHD NIH HHS L40 HD103048
6 · The paper itself

Abstract

Exposure to early life adversity (ELA) is associated with increased externalizing symptoms (e.g., aggression and oppositionality), internalizing symptoms (e.g., withdrawal and anxiety), and biological indicators of accelerated aging (e.g., telomere length) in childhood. However, little is known about how distinct dimensions of ELA, such as threat and deprivation, impact youth psychobiological outcomes. The present study includes data from the Future of Families and Child Wellbeing Study (FFCWS), a large population-based, birth cohort study of majority (approximately 75%) racial and ethnic minority youth born between 1998 and 2000 across 20 large cities in the United States. The present study includes a subset of the original sample (N = 2,483, 51.6% male) who provided genetic data at age 9. First, confirmatory factor analyses were conducted, which revealed four distinct dimensions of ELA (home threat, community threat, neglect, and lack of stimulation) when children were age 3. Second, latent profile analyses identified an eight-profile solution based on unique patterns of the four ELA dimensions. Lastly, latent profiles were used to predict associations with child psychological and biological outcomes at age 9. Results suggest that exposure to specific combinations of ELA is differentially associated with internalizing and externalizing behaviors in childhood, but not with telomere length. Findings have implications for personalized early intervention and prevention efforts aimed at reducing ELA exposure to protect against downstream negative mental health outcomes for diverse youth.

Indexed as

Adverse Childhood ExperiencesNeurosciencesAdolescentChildChild, PreschoolCohort StudiesEthnicityFemaleHumansMaleMinority Groupsdeprivationexternalizinginternalizingtelomere lengththreat

Identifiers

PMID37195493
PMCPMC11892347

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.