Evidence map›Paper›PMID 37195430›Full record

ArticleJournal of medical systems2023

From Data to Wisdom: Biomedical Knowledge Graphs for Real-World Data Insights.

Katrin Hänsel, Sarah N Dudgeon, Kei-Hoi Cheung, Thomas J S Durant, Wade L Schulz

Abstract readLetter
In one paragraph

Article in Journal of medical systems, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Katrin HänselDepartment of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.
Sarah N DudgeonDepartment of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.
Kei-Hoi CheungSection of Biomedical Informatics, Department of Emergency Medicine, Yale School of Medicine, 55 Park Street, PS 210, New Haven, CT, 06510, USA.
Thomas J S DurantDepartment of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.
Wade L SchulzDepartment of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA. wade.schulz@yale.edu.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
IMMUNOHEMATOLOGY/TRANSFUSION MEDICINE RESEARCH TRAININGT32HL007974 · NHLBI · YALE UNIVERSITY · PI JEANNE E HENDRICKSON, Diane S Krause · 2001 to 2026
$8.1M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS T32 HL007974
6 · The paper itself

Abstract

Graph data models are an emerging approach to structure clinical and biomedical information. These models offer intriguing opportunities for novel approaches in healthcare, such as disease phenotyping, risk prediction, and personalized precision care. The combination of data and information in a graph model to create knowledge graphs has rapidly expanded in biomedical research, but the integration of real-world data from the electronic health record has been limited. To broadly apply knowledge graphs to EHR and other real-world data, a deeper understanding of how to represent these data in a standardized graph model is needed. We provide an overview of the state-of-the-art research for clinical and biomedical data integration and summarize the potential to accelerate healthcare and precision medicine research through insight generation from integrated knowledge graphs.

Indexed as

AlgorithmsBiomedical ResearchHumansPattern Recognition, AutomatedPhenotypePrecision MedicineBiomedical knowledge graphClinical outcome predictionHealthcare applicationsMedical knowledge curation

Identifiers

PMID37195430
PMCPMC10191934

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.