Evidence map›Paper›PMID 37195233›Full record

ArticleJournal of bacteriology2023

The ComRS-SigX Pathway Regulates Natural Transformation in Streptococcus ferus.

Britta E Rued, Michael J Federle

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. The MutRS quorum-sensing system controls lantibiotic mutacin production in the human pathogenProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Britta E RuedDepartment of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID 0000-0003-3178-4269
Michael J FederleDepartment of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID 0000-0002-4554-543X
University of Illinois Chicago · US

Funding

Mechanistic Dissection of Pheromone-Dependent Regulation of Group A StreptococcalR01AI091779 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FEDERLE, MICHAEL J · 2011 to 2021
$3.9M
IRACDA at University of Illinois at ChicagoK12GM139186 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BURDETTE, JOANNA E, NONN, LARISA · 2020 to 2024
$3.6M
NIAID NIH HHS R01 AI091779NIGMS NIH HHS K12 GM139186
6 · The paper itself

Abstract

The ability to take up and incorporate foreign DNA via natural transformation is a well-known characteristic of some species of Streptococcus, and is a mechanism that rapidly allows for the acquisition of antibacterial resistance. Here, we describe that the understudied species Streptococcus ferus is also capable of natural transformation and uses a system analogous to that identified in Streptococcus mutans. S. mutans natural transformation is under the control of the alternative sigma factor

Indexed as

Bacterial ProteinsStreptococcus mutansDNA Transformation CompetenceGene Expression Regulation, BacterialPeptidesStreptococcusBacterial ProteinsPeptidescompetenceoral bacteriapheromonequorum sensingtransformation

Identifiers

PMID37195233
PMCPMC10294618
OpenAlexW4376872268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.