Evidence map›Paper›PMID 37195209›Full record

ArticleMicrobiology spectrum2023

Characterization of a Nonagglutinating Toxigenic Vibrio cholerae Isolate.

Lori M Gladney, Taylor Griswold, Maryann Turnsek, Monica S Im, Michele M B Parsons, Lee S Katz, Cheryl L Tarr, Christine C Lee

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lori M GladneyEnteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Taylor GriswoldEnteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Maryann TurnsekEnteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Monica S ImEnteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Michele M B ParsonsDivision of Global Health Protection, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Lee S KatzEnteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Cheryl L TarrEnteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Christine C LeeEnteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0003-4540-1628

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxigenic Vibrio cholerae serogroup O1 is the etiologic agent of the disease cholera, and strains of this serogroup are responsible for pandemics. A few other serogroups have been found to carry cholera toxin genes-most notably, O139, O75, and O141-and public health surveillance in the United States is focused on these four serogroups. A toxigenic isolate was recovered from a case of vibriosis from Texas in 2008. This isolate did not agglutinate with any of the four different serogroups' antisera (O1, O139, O75, or O141) routinely used in phenotypic testing and did not display a rough phenotype. We investigated several hypotheses that might explain the recovery of this potential nonagglutinating (NAG) strain using whole-genome sequencing analysis and phylogenetic methods. The NAG strain formed a monophyletic cluster with O141 strains in a whole-genome phylogeny. Furthermore, a phylogeny of

Indexed as

CholeraVibrio choleraeVibrio InfectionsHumansO AntigensPhylogenyUnited StatesO AntigensMAGNAGnonagglutinating Vibrio straintoxigenic Vibrio surveillanceUSGC Vibrio choleraeVibrio cholerae

Identifiers

PMID37195209
PMCPMC10269536

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.