Evidence map›Paper›PMID 37195130›Full record

ArticleJournal of proteome research2023

ATP-Coated Dual-Functionalized Titanium(IV) IMAC Material for Simultaneous Enrichment and Separation of Glycopeptides and Phosphopeptides.

Danqing Wang, Junfeng Huang, Haoran Zhang, Min Ma, Meng Xu, Yusi Cui, Xudong Shi, Lingjun Li

Open access · greenAbstract read
In one paragraph

Article in Journal of proteome research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. High-Throughput Proteomic and Glycoproteomic Analyses in Benign Prostatic Hyperplasia.Journal of the American Society for Mass Spectrometry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Danqing WangDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0000-0001-8080-9675
Junfeng HuangSchool of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.ORCID 0000-0002-1672-3751
Haoran ZhangDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Min MaSchool of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Meng XuDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Yusi CuiDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Xudong ShiDepartment of Surgery, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Lingjun LiDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0000-0003-0056-3869
University of Wisconsin–Madison · US

Funding

Mass Spectrometric Studies of Neuropeptides in FeedingR01DK071801 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI LINGJUN LI · 2006 to 2026
$6.7M
Creating a region- specific biomolecular atlas of the brain of Alzheimer’s diseaseR01AG078794 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI LINGJUN LI, Luigi Puglielli · 2022 to 2026
$3.7M
Di-Leu-enabled multiplexed quantitation for biomarker discovery and validation in Alzheimer's diseaseRF1AG052324 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI LI, LINGJUN · 2018 to 2018
$2.4M
Acquisition of a High-Field Dual Source FTICR-MS for Pharmaceutical ResearchS10RR029531 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI LI, LINGJUN · 2011 to 2011
$2.1M
Acquisition of a Dual-Source, High-Performance, Ion Mobility, Quadrupole Time-of-Flight Mass Spectrometry System for Biomedical Research at UW-MadisonS10OD028473 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI LI, LINGJUN · 2021 to 2021
$1.3M
Acquisition of a High Resolution High Speed MALDI Mass Spectrometer for Biomedical Research at UW-MadisonS10OD025084 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI LI, LINGJUN · 2018 to 2018
$598k
Probing Protein Structural Changes in Alzheimers DiseaseR21AG065728 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI LI, LINGJUN · 2020 to 2020
$420k
NCRR NIH HHS S10 RR029531NIA NIH HHS R01 AG078794NIA NIH HHS R21 AG065728NIA NIH HHS RF1 AG052324NIDDK NIH HHS R01 DK071801NIH HHS S10 OD025084NIH HHS S10 OD028473
6 · The paper itself

Abstract

Protein glycosylation and phosphorylation are two of the most common post-translational modifications (PTMs), which play an important role in many biological processes. However, low abundance and poor ionization efficiency of phosphopeptides and glycopeptides make direct MS analysis challenging. In this study, we developed a hydrophilicity-enhanced bifunctional Ti-IMAC (IMAC: immobilized metal affinity chromatography) material with grafted adenosine triphosphate (denoted as epoxy-ATP-Ti

Indexed as

PhosphopeptidesTitaniumAnimalsChromatography, AffinityGlycopeptidesHeLa CellsHumansImidazolesMiceGlycopeptidesimidazoleacetic acidImidazolesPhosphopeptidesTitaniumenrichmentglycoproteomicsimmobilized metal affinity chromatographymaterialsphosphoproteomicspost-translational modifications

Identifiers

PMID37195130
PMCPMC11138137
OpenAlexW4376872460

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.