Evidence map›Paper›PMID 37194980›Full record

ArticleBioEssays : news and reviews in molecular, cellular and developmental biology2023

BENDing with Polycomb in pluripotency and cancer.

Abid Khan, Supriya Prasanth

Abstract read
In one paragraph

Article in BioEssays : news and reviews in molecular, cellular and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Abid KhanDepartment of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina, USA.
Supriya PrasanthDepartment of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.ORCID 0000-0002-3735-7498

Funding

Regulation of genomic stability by ORCR01GM125196 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI PRASANTH, SUPRIYA G · 2018 to 2021
$1.3M
Role of ORCA in DNA replicationR01GM099669 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI PRASANTH, SUPRIYA G · 2012 to 2016
$1.3M
NIGMS NIH HHS R01 GM099669NIGMS NIH HHS R01 GM125196NIH HHS GM125196
6 · The paper itself

Abstract

Three recent publications on BEND3 firmly establish its role as a novel sequence-specific transcription factor that is essential for PRC2 recruitment and maintenance of pluripotency. Here, we briefly review our current understanding of the BEND3-PRC2 axis in the regulation of pluripotency and also explore the possibility of a similar connection in cancer.

Indexed as

NeoplasmsPolycomb Repressive Complex 2Gene Expression RegulationHumansPolycomb-Group ProteinsPolycomb-Group ProteinsPolycomb Repressive Complex 2BEND3EZH2pluripotencyPRC2stem cells

Identifiers

PMID37194980
PMCPMC10524657

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.