Evidence map›Paper›PMID 37194664›Full record

ArticleThe Laryngoscope2023

Detecting Mild Phonotrauma in Daily Life.

Jarrad H Van Stan, James Burns, Tiffiny Hron, Steven Zeitels, Bharat A Panuganti, Phillip R Purnell, Daryush D Mehta, Robert E Hillman, Hamzeh Ghasemzadeh

Abstract read
In one paragraph

Article in The Laryngoscope, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jarrad H Van StanMassachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0001-8932-3276
James BurnsMassachusetts General Hospital, Boston, Massachusetts, USA.
Tiffiny HronMassachusetts General Hospital, Boston, Massachusetts, USA.
Steven ZeitelsMassachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0001-6311-8389
Bharat A PanugantiUniversity of Alabama at Birmingham, Birmingham, Alabama, USA.
Phillip R PurnellRutgers University, New Brunswick, New Jersey, USA.
Daryush D MehtaMassachusetts General Hospital, Boston, Massachusetts, USA.
Robert E HillmanMassachusetts General Hospital, Boston, Massachusetts, USA.
Hamzeh GhasemzadehMassachusetts General Hospital, Boston, Massachusetts, USA.

Funding

Use of ambulatory biofeedback to improve behavioral treatment of vocal hyperfunctionP50DC015446 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI Jarrad Van Stan · 2017 to 2026
$25.5M
Advanced Research Training in Communication Sciences and DisordersT32DC013017 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Cara E. Stepp · 2016 to 2026
$4.9M
Ambulatory monitoring of vocal function to improve voice disorder assessmentR33DC011588 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI HILLMAN, ROBERT E · 2012 to 2015
$2.3M
Ambulatory monitoring of vocal function to improve voice disorder assessmentR21DC011588 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI HILLMAN, ROBERT E · 2011 to 2011
$264k
NIDCD NIH HHS P50 DC015446NIDCD NIH HHS R21 DC011588NIDCD NIH HHS R33 DC011588NIDCD NIH HHS T32 DC013017
6 · The paper itself

Abstract

objectiveThe aim of this study was to gain quantitative insights into the role of daily voice use associated with mild phonotrauma via the Daily Phonotrauma Index (DPI), a measure derived from neck-surface acceleration magnitude (NSAM) and difference between the first two harmonic magnitudes (H1 - H2).

methodsAn ambulatory voice monitor recorded weeklong voice use for 151 female patients with phonotraumatic vocal hyperfunction (PVH) and 181 female vocally healthy controls. Three laryngologists rated phonotrauma severity from each patient's laryngoscopy. Mixed generalized linear models evaluated the accuracy, sensitivity, and specificity of the original DPI trained on all patients versus a mild DPI version trained on only patients rated with mild phonotrauma. Individual contribution of NSAM and H1 - H2 to each DPI model was also evaluated.

resultsReliability across the laryngologists' phonotrauma ratings was moderate (Fleiss κ = 0.41). There were 70, 69, and 12 patients with mild, moderate, and severe phonotrauma, respectively. The mild DPI, compared to the original DPI, correctly classified more patients with mild phonotrauma (Cohen's d = 0.9) and less controls (d = -0.9) and did not change in overall accuracy. H1 - H2 contributed less to mild phonotrauma classification than NSAM for mild DPI.

conclusionsCompared with the original DPI, the mild DPI exhibited higher sensitivity to mild phonotrauma and lower specificity to controls, but the same overall classification accuracy. These results support the mild DPI as a promising detector of early phonotrauma and that NSAM may be associated with early phonotrauma, and H1 - H2 may be a biomarker associated with vocal fold vibration in the presence of lesions. LEVEL OF EVIDENCE: Level 4, case-control study Laryngoscope, 133:3094-3099, 2023.

Indexed as

VoiceVoice DisordersCase-Control StudiesFemaleHumansReproducibility of ResultsVocal Cordsvoice assessment measuresvoice dysphonia

Identifiers

PMID37194664
PMCPMC10592567

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.