Evidence map›Paper›PMID 37194422›Full record

ArticleJournal of veterinary internal medicine

Serum insulin concentration in dogs with insulinoma as a clinical marker for presence of metastasis at the time of diagnosis.

Andrea Petrelli, Alexander J German, Erin M O'Connell, Paolo Silvestrini

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Andrea PetrelliInstitute of Veterinary Science, University of Liverpool, Neston, UK.ORCID https://orcid.org/0000-0003-1788-8299
Alexander J GermanInstitute of Veterinary Science, University of Liverpool, Neston, UK.ORCID https://orcid.org/0000-0002-3017-7988
Erin M O'ConnellInstitute of Veterinary Science, University of Liverpool, Neston, UK.
Paolo SilvestriniSchool of Veterinary Medicine, University of Pennsylvania, Pennsylvania, Philadelphia, USA.ORCID https://orcid.org/0000-0003-3671-5350
University of Liverpool · GBUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInformation regarding serum insulin concentration in dogs newly diagnosed with insulinoma and its association with clinical stage and survival time is lacking.

objectiveExamine association between serum insulin concentration and survival and clinical disease stage in dogs with insulinoma. ANIMALS: Fifty-nine client-owned dogs with a diagnosis of insulinoma from 2 referral hospitals.

methodRetrospective observational study. The χ

resultsMedian serum insulin concentration was 33 mIU/L (range, 8-200 mIU/L) in dogs with World Health Organization (WHO) stage I disease and 45 mIU/L (range, 12-213 mIU/L) in dogs with WHO stage II and III disease. No difference was found in the proportion of dogs with increased insulin concentration with or without metastasis (P = .09). No association was identified between insulin concentration and survival (P = .63), and between dogs grouped by insulin concentration and survival (P = .51). CONCLUSIONS AND CLINICAL IMPORTANCE: Serum insulin concentrations were not different between dogs with or without metastasis at diagnosis. The degree of insulinemia does not provide further information regarding the stage of the disease and is not associated with survival time in dogs with insulinoma.

Indexed as

Dog DiseasesInsulinomaPancreatic NeoplasmsAnimalsBiomarkersDogsInsulinRetrospective StudiesBiomarkersInsulininsulinemiaprognosisstagesurvival

Identifiers

PMID37194422
PMCPMC10229349
OpenAlexW4376871453

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.