Evidence map›Paper›PMID 37194369›Full record

ArticleThe Journal of physiology2023

Modulation of dorsal premotor cortex differentially influences I-wave excitability in primary motor cortex of young and older adults.

Wei-Yeh Liao, George M Opie, Ulf Ziemann, John G Semmler

Open access · hybridAbstract read
In one paragraph

Article in The Journal of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Wei-Yeh LiaoDiscipline of Physiology, School of Biomedicine, The University of Adelaide, Adelaide, Australia.ORCID 0000-0002-8912-9796
George M OpieDiscipline of Physiology, School of Biomedicine, The University of Adelaide, Adelaide, Australia.ORCID 0000-0001-7771-7569
Ulf ZiemannDepartment of Neurology & Stroke, Eberhard Karls University of Tübingen, Tübingen, Germany.ORCID 0000-0001-8372-3615
John G SemmlerDiscipline of Physiology, School of Biomedicine, The University of Adelaide, Adelaide, Australia.ORCID 0000-0003-0260-8047
The University of Adelaide · AUHertie Institute for Clinical Brain Research · DE

Funding

Australian Research Council Discovery Project DP200101009National Health and Medical Research Council APP1139723
6 · The paper itself

Abstract

Previous research using transcranial magnetic stimulation (TMS) has demonstrated weakened connectivity between dorsal premotor cortex (PMd) and motor cortex (M1) with age. While this alteration is probably mediated by changes in the communication between the two regions, the effect of age on the influence of PMd on specific indirect (I) wave circuits within M1 remains unclear. The present study therefore investigated the influence of PMd on early and late I-wave excitability in M1 of young and older adults. Twenty-two young (mean ± SD, 22.9 ± 2.9 years) and 20 older (66.6 ± 4.2 years) adults participated in two experimental sessions involving either intermittent theta burst stimulation (iTBS) or sham stimulation over PMd. Changes within M1 following the intervention were assessed with motor-evoked potentials (MEPs) recorded from the right first dorsal interosseous muscle. We applied posterior-anterior (PA) and anterior-posterior (AP) current single-pulse TMS to assess corticospinal excitability (PA

Indexed as

Cortical ExcitabilityMotor CortexAgedElectromyographyEvoked Potentials, MotorHumansMusclesTranscranial Magnetic StimulationYoung Adultageingdorsal premotor cortextranscranial magnetic stimulation

Identifiers

PMID37194369
PMCPMC10952229
OpenAlexW4376872046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.