Evidence map›Paper›PMID 37194319›Full record

ArticleASN neuro

Sex-Dimorphic Octadecaneuropeptide (ODN) Regulation of Ventromedial Hypothalamic Nucleus Glucoregulatory Neuron Function and Counterregulatory Hormone Secretion.

Karen P Briski, Prabhat R Napit, Abdulrahman Alhamyani, Jérôme Leprince, A S M Hasan Mahmood

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ASN neuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Karen P BriskiSchool of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA, USA.ORCID 0000-0002-7648-1395
Prabhat R NapitSchool of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA, USA.
Abdulrahman AlhamyaniSchool of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA, USA.
Jérôme LeprinceNeuronal and Neuroendocrine Differentiation and Communication Laboratory, Normandy University, INSERM U1239, PRIMACEN, Rouen, France.ORCID 0000-0002-7814-9927
A S M Hasan MahmoodSchool of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA, USA.
University of Louisiana at Monroe · USInserm · FR

Funding

Estradiol Regulation of Hypothalamic Astrocyte GlycogenR01DK109382 · NIDDK · UNIVERSITY OF LOUISIANA AT MONROE · PI BRISKI, KAREN P · 2016 to 2020
$1.7M
NIDDK NIH HHS R01 DK109382
6 · The paper itself

Abstract

Central endozepinergic signaling is implicated in glucose homeostasis. Ventromedial hypothalamic nucleus (VMN) metabolic monitoring governs glucose counter-regulation. VMN glucose-stimulatory nitric oxide (NO) and glucose-inhibitory γ-aminobutyric acid (GABA) neurons express the energy gauge 5'-AMP-activated protein kinase (AMPK). Current research addresses the premise that the astrocyte glio-peptide octadecaneuropeptide (ODN) imposes sex-dimorphic control of metabolic sensor activity and neurotransmitter signaling in these neurons. The ODN G-protein coupled-receptor antagonist cyclo

Indexed as

HypoglycemiaVentromedial Hypothalamic NucleusAMP-Activated Protein KinasesAnimalsDiazepam Binding InhibitorGlucoseGlycogenHormonesMaleNeuronsNeuropeptidesNorepinephrinePeptide FragmentsRatsRats, Sprague-DawleyAMP-Activated Protein KinasesDiazepam Binding Inhibitordiazepam binding inhibitor (33-50)GlucoseGlycogenHormonesNeuropeptidesNorepinephrinePeptide FragmentsAMPKcyclo(1−8)[DLeu5]OPinsulin-induced hypoglycemianeuronal nitric oxide synthaseoctadecaneuropeptidesex differencesventromedial hypothalamic nucleus

Identifiers

PMID37194319
PMCPMC10196551
OpenAlexW4376871284

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.