Evidence map›Paper›PMID 37194263›Full record

ArticleCanadian journal of psychiatry. Revue canadienne de psychiatrie2023

Do Anxiety Symptoms Mediate the Association Between Cannabis Use Frequency and Psychotic-Like Experiences in Emerging Adult Undergraduates?

Haley C R Bernusky, Philip G Tibbo, Patricia J Conrod, Fakir Md Yunus, Matthew T Keough, Kara D Thompson, Marvin D Krank, Allyson F Hadwin, Sherry H Stewart

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Haley C R BernuskyDepartment of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.ORCID 0000-0001-8996-0523
Philip G TibboDepartment of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
Patricia J ConrodDépartement de psychiatrie et d'addictologie, Université de Montréal, Montréal, Québec, Canada.
Fakir Md YunusDepartment of Psychology and Neuroscience, Dalhousie University, Halifax, Nova Scotia, Canada.
Matthew T KeoughDepartment of Psychology, York University, North York, Ontario, Canada.
Kara D ThompsonDepartment of Psychology, St. Francis Xavier University, Antigonish, Nova Scotia, Canada.
Marvin D KrankDepartment of Psychology, University of British Columbia, Kelowna, British Columbia, Canada.
Allyson F HadwinDepartment of Educational Psychology and Leadership Studies, University of Victoria, Victoria, British Columbia, Canada.
Sherry H StewartDepartment of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
Dalhousie University · CASt. Francis Xavier University · CAUniversité de Montréal · CAUniversity of British Columbia · CAUniversity of Victoria · CAYork University · CA

Funding

CIHR CA7-170130
6 · The paper itself

Abstract

objectiveCannabis is commonly used by Canadian emerging adults (ages 18-25 years), many of whom attend post-secondary institutions. Frequent cannabis use is linked with psychotic-like experiences (PLEs); however, the exact nature of this association remains unclear. Anxiety symptoms may mediate this association, as they are prevalent in emerging adults and have been independently linked with both cannabis use and PLEs. Past work found that anxiety mediated the association between cannabis use frequency and attenuated positive psychotic symptoms (further along the psychosis continuum than PLEs), however this research had yet to be validated in the Canadian population, and trait rather than state anxiety (frequency of anxiety symptoms) was studied. Thus, our primary objective was to examine if anxiety symptoms mediated the association between cannabis use frequency and PLEs in Canadian emerging adult undergraduates. Despite known sex differences in cannabis use, expression of anxiety, and PLEs, past work did not evaluate the potential impact of biological sex on the anxiety-mediated model, and thus is the secondary objective of the present study.

methods1,266 first-/second-year emerging adult undergraduates from five Canadian universities provided cross-sectional, self-report survey data in fall 2021 semester. Validated measures of cannabis use frequency, anxiety, and PLEs were administered.

resultsPath analyses supported mediation from cannabis use to PLEs through anxiety (

conclusionsAnxiety symptoms mediated the association between cannabis use and PLEs in emerging adults regardless of their biological sex. Assuming replication in prospective research, results highlight anxiety as an important intervention target in frequent cannabis-using emerging adults, to potentially prevent development/worsening of PLEs, and in turn psychotic illness.

Indexed as

CannabisPsychotic DisordersAdolescentAdultAnxietyCanadaCross-Sectional StudiesFemaleHumansMaleProspective StudiesSurveys and QuestionnairesYoung Adultanxietybiological sexcannabisconditional process modelemerging adultsmediationmoderationpath analysispsychotic-like experiences

Identifiers

PMID37194263
PMCPMC10590089
OpenAlexW4376872704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.