Evidence map›Paper›PMID 37193944›Full record

ArticleBMC microbiology2023

Bifunctional protein ArsR

Congcong Li, Gongli Zong, Xi Chen, Meixia Tan, Wenhui Gao, Jiafang Fu, Peipei Zhang, Bing Wang, Guangxiang Cao

Open access · goldAbstract read
In one paragraph

Article in BMC microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Congcong LiShandong Quancheng Test & Technology Limited Company, Ji'nan, 250101, China.
Gongli ZongBiomedical Sciences College & Shandong Medicinal Biotechnology Centre, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, 250062, China.
Xi ChenBiomedical Sciences College & Shandong Medicinal Biotechnology Centre, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, 250062, China.
Meixia TanBiomedical Sciences College & Shandong Medicinal Biotechnology Centre, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, 250062, China.
Wenhui GaoBiomedical Sciences College & Shandong Medicinal Biotechnology Centre, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, 250062, China.
Jiafang FuBiomedical Sciences College & Shandong Medicinal Biotechnology Centre, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, 250062, China.
Peipei ZhangBiomedical Sciences College & Shandong Medicinal Biotechnology Centre, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, 250062, China.
Bing Wang *Shandong Quancheng Test & Technology Limited Company, Ji'nan, 250101, China. 345807969@qq.com.
Guangxiang Cao *Biomedical Sciences College & Shandong Medicinal Biotechnology Centre, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, 250062, China. caoguangxiang@sdfmu.edu.cn.
Shandong First Medical University · CNAnalysis and Testing Centre · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArsenic (As) with various chemical forms, including inorganic arsenic and organic arsenic, is the most prevalent water and environmental toxin. This metalloid occurs worldwide and many of its forms, especially arsenite [As(III)], cause various diseases including cancer. Organification of arsenite is an effective way for organisms to cope with arsenic toxicity. Microbial communities are vital contributors to the global arsenic biocycle and represent a promising way to reduce arsenite toxicity.

methodsBrevundimonas sp. M20 with arsenite and roxarsone resistance was isolated from aquaculture sewage. The arsHRNBC cluster and the metRFHH operon of M20 were identified by sequencing. The gene encoding ArsR/methyltransferase fusion protein, arsR

resultsThe minimum inhibitory concentration of the roxarsone resistant strain Brevundimonas sp. M20 to arsenite was 4.5 mM. A 3,011-bp arsenite resistance ars cluster arsHRNBC and a 5649-bp methionine biosynthesis met operon were found on the 3.315-Mb chromosome. Functional prediction analyses suggested that ArsR

conclusionsWe conclude that ArsR

Indexed as

ArsenicArsenicalsArsenitesRoxarsoneBacterial ProteinsBase SequenceEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialMethionineMethylationMethyltransferasesOperonTrans-ActivatorsArsenicArsenicalsarseniteArsenitesArsR protein, E coliBacterial ProteinsEscherichia coli ProteinsMethionineMethyltransferasesRoxarsoneTrans-ActivatorsArs clusterArsenic resistanceBifunctional proteinBrevundimonas sp.Inorganic arsenic detoxify

Identifiers

PMID37193944
PMCPMC10190100
OpenAlexW4376865445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.