Evidence map›Paper›PMID 37193817›Full record

ArticleScientific reports2023

Differences in optic nerve head structure between acute angle-closure glaucoma and open-angle glaucoma.

Jeong Han Kong, Sung Pyo Park, Kyeong Ik Na

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Ocular changes as potential biomarkers for early diagnosis of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jeong Han KongDepartment of Ophthalmology, Kangdong Sacred Heart Hospital, 150, Seongan-ro, Gangdong-gu, Seoul, 05355, South Korea.
Sung Pyo ParkDepartment of Ophthalmology, Kangdong Sacred Heart Hospital, 150, Seongan-ro, Gangdong-gu, Seoul, 05355, South Korea.
Kyeong Ik NaDepartment of Ophthalmology, Kangdong Sacred Heart Hospital, 150, Seongan-ro, Gangdong-gu, Seoul, 05355, South Korea. hypocenter@naver.com.
Kangdong Sacred Heart Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to compare the optic nerve head (ONH) structure in acute angle-closure glaucoma (AACG) and open-angle glaucoma (OAG) to investigate the differences in glaucomatous damage. The AACG and OAG eyes were matched with regard to global retinal nerve fiber layer thickness (RNFLT). AACG eyes were divided into two subgroups based on the presence of ONH swelling at the onset of AACG. RNFLT, Bruch's membrane opening-minimum rim width (BMO-MRW), and Bruch's membrane opening-minimum rim area (BMO-MRA) were analyzed. Global RNFLT values were similar in AACG and OAG groups, but lower than in the healthy group (P < 0.001). The global BMO-MRW and total BMO-MRA were significantly higher in AACG than in OAG group (P < 0.001, respectively). AACG showed similar global BMO-MRW and total BMO-MRA, irrespective of the presence or absence of ONH swelling, while AACG with ONH swelling was associated with significantly thinner global RNFLT compared to AACG without ONH swelling (P < 0.006). The result of differences in ONH structure between the OAG and AACG, especially the AACG with ONH swelling at the onset of AACG, suggests that the mechanisms of optic nerve damage in the two diseases are different.

Indexed as

Glaucoma, Angle-ClosureGlaucoma, Open-AngleOptic DiskBruch MembraneHumansIntraocular PressureNerve FibersRetinal Ganglion CellsTomography, Optical CoherenceVisual Fields

Identifiers

PMID37193817
PMCPMC10188438
OpenAlexW4376871235

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.