ArticleScientific reports2023
Dual quantum cascade lasers for noninvasive glucose detection using photoacoustic spectroscopy.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Photoacoustic Resonators for Non-Invasive Blood Glucose Detection Through Photoacoustic Spectroscopy: A Systematic Review.Sensors (Basel, Switzerland) · 2024Pooled it
- A Single-Wavelength Near-Infrared Photoacoustic Spectroscopy for Noninvasive Glucose Detection Using Machine Learning.Bioengineering (Basel, Switzerland) · 2026Article
- Photoacoustic Noninvasive Blood Glucose Monitoring: A Review of Systems and Strategies for Robust Glucose Concentration Estimation, with Perspectives on Miniaturization and Wearability.Sensors (Basel, Switzerland) · 2026Review
- The Optimization of a T-Cell Resonator: Towards Highly Sensitive Photoacoustic Spectroscopy for Noninvasive Blood Glucose Detection.Biosensors · 2025Article
- Clinical evaluation of a polarization-based optical noninvasive glucose sensing system.Scientific reports · 2025Article
- Quantitative blood glucose detection influenced by various factors based on the fusion of photoacoustic temporal spectroscopy with deep convolutional neural networks.Biomedical optics express · 2024Article
- Non-invasive measurements of blood glucose levels by time-gating mid-infrared optoacoustic signals.Nature metabolism · 2024Article
- Progress and Perspectives of Mid-Infrared Photoacoustic Spectroscopy for Non-Invasive Glucose Detection.Biosensors · 2023Review
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The combination of mid-infrared and photoacoustic spectroscopy has shown promising developments as a substitute for invasive glucose detection technology. A dual single-wavelength quantum cascade laser system has been developed using photoacoustic spectroscopy for noninvasive glucose monitoring. Biomedical skin phantoms with similar properties to human skin have been prepared with blood components at different glucose concentrations as test models for the setup. The detection sensitivity of the system has been improved to ± 12.5 mg/dL in the hyperglycemia blood glucose ranges. An ensemble machine learning classifier has been developed to predict the glucose level in the presence of blood components. The model, which was trained with 72,360 unprocessed datasets, achieved a 96.7% prediction accuracy with 100% of the predicted data located in zones A and B of Clarke's error grid analysis. These findings fulfill both the US Food and Drug Administration and Health Canada requirements for glucose monitors.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.