Evidence map›Paper›PMID 37193762›Full record

ArticleCommunications biology2023

GDE7 produces cyclic phosphatidic acid in the ER lumen functioning as a lysophospholipid mediator.

Keisuke Kitakaze, Hanif Ali, Raiki Kimoto, Yasuhiro Takenouchi, Hironobu Ishimaru, Atsushi Yamashita, Natsuo Ueda, Tamotsu Tanaka, Yasuo Okamoto, Kazuhito Tsuboi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Keisuke KitakazeDepartment of Pharmacology, Kawasaki Medical School, Kurashiki, Okayama, Japan. kitakaze@med.kawasaki-m.ac.jp.ORCID 0000-0002-4852-1257
Hanif AliGraduate School of Technology, Industrial and Social Sciences, Tokushima University, Tokushima, Japan.
Raiki KimotoDepartment of Pharmacology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Yasuhiro TakenouchiDepartment of Pharmacology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Hironobu IshimaruDepartment of Pharmacology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Atsushi YamashitaLaboratory of Biological Chemistry, Faculty of Pharma-Science, Teikyo University, Tokyo, Japan.
Natsuo UedaDepartment of Biochemistry, Kagawa University School of Medicine, Miki, Kagawa, Japan.
Tamotsu TanakaGraduate School of Technology, Industrial and Social Sciences, Tokushima University, Tokushima, Japan.
Yasuo OkamotoDepartment of Pharmacology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Kazuhito TsuboiDepartment of Pharmacology, Kawasaki Medical School, Kurashiki, Okayama, Japan. ktsuboi@med.kawasaki-m.ac.jp.ORCID 0000-0002-4943-944X
Kawasaki Medical School · JPTokushima University · JPKagawa University · JPTeikyo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclic phosphatidic acid (cPA) is a lipid mediator, which regulates adipogenic differentiation and glucose homeostasis by suppressing nuclear peroxisome proliferator-activated receptor γ (PPARγ). Glycerophosphodiesterase 7 (GDE7) is a Ca

Indexed as

Phosphatidic AcidsPPAR gammaAnimalsEndoplasmic ReticulumHumansLysophospholipidsMicePhosphoric Diester HydrolasesGDE7 protein, mouseglycerophosphodiester phosphodiesteraseLysophospholipidsPhosphatidic AcidsPhosphoric Diester HydrolasesPPAR gamma

Identifiers

PMID37193762
PMCPMC10188492
OpenAlexW4376872782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.